Hi Linda,
I, too, had read about Blackwell's study while on tamoxifen. I was dx'd as er/pr+ on my original dx in April, 2001...only to discover another isolated tumor that was er/pr- when they went back in to clear the margins after the lumpectomy. At that point it was a bit "controversial"...was I - or +? My onc's decided that since the orig tumor was definately + that I should go on the tamoxifen, which I did for just over a year when I discovered a local recurrence in the same breast (2 years after orig dx). Further scans, etc. revealed a 7cm lesion on my liver (reduced after only 3 rounds of taxotere/herceptin to 3cm!). The recurrent bc also tested er/pr-...I was immediately taken off tamoxifen. I, too, have this theory that the tamoxifen was a culprit in my recurrence...but, of course, who knows really. I'm always looking for the reason "why", as I guess we all do. Have you discussed with your onc the possibility of putting you on one of the inhibitors instead of tamoxifen? I remember mine telling me that it was "unusual" to be her2+ AND er/pr+...I think they are still learning as we go, as far as the her2 thing is concerned. Best of luck to you!!
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