HonCode

Go Back   HER2 Support Group Forums > her2group
Register Gallery FAQ Members List Calendar Search Today's Posts Mark Forums Read

Reply
 
Thread Tools Display Modes
Old 02-25-2009, 06:34 AM   #61
Brenda S
Senior Member
 
Join Date: Apr 2008
Posts: 69
Smile Positive thoughts!

MaryAnne,
I understand your "worries" I'm entering the final phase of my "battle" and recently had a scare. I had terrible bone pain--still do-- and was almost convinced I'd fallen victim to bone mets. After a very worrying few weeks I had a complete, full body bone scan. The results came bach CLEAR. I'm confident your results will be the same. Keep the faith. I've said a prayer for you, and will do so again.
Stay positive!!
Warmest wishes,
Brenda
__________________
Diagnosed 3/08 at age 57
1.1cm tumor, ER-PR-, Her2 3+(rt side)

Grade 2
Node negative
clean margins
Stage 1
lumpectomy 4/08
Mammocite Radiation 4/08
Will begin TCH Chemo 5/08
TCH 3 week cycle for 6 cycles
Herceptin alone for 18 more treatments on a 3 week cycle
Total chemo 12 months
Neulasta 24 hours after each cycle
Brenda S is offline   Reply With Quote
Old 02-25-2009, 03:39 PM   #62
harrie
Senior Member
 
harrie's Avatar
 
Join Date: Mar 2007
Location: Hilo, Hawaii
Posts: 1,867
RE: Jackie's recent post on the Hans Chinese. Very interesting info Jackie. If it is true that they are genetically related to the Jews like that, it puts that genetic study into a very different light in the statement that Asians are understated in the predisposition to the BRCA1/2 gene. No wonder the results came out like that.

Brenda, I am very happy to hear of your bone scan results!! WHEW!!!
My results were good also. Just what I wanted to hear.
Maryanne
__________________
*** MARYANNE *** aka HARRIECANARIE

1993: right side DCIS, lumpectomy, rads
1999: left side DCIS, lumpectomy, rads, tamoxifen

2006:
BRCA 2 positive
Stage I, invasive DCIS (6mm x 5mm)
Grade: intermediate
sentinal node biopsy: neg
HER2/neu amplified 4.7
ER+/PR+
TOPO II neg
Oncotype dx 20
Bilat mastectomy with DIEP flap reconstruction
oophorectomy

2007:
6 cycles TCH (taxotere, carboplatin, herceptin)
finished 1 yr herceptin 05/07
Arimidex, stopped after almost 1 yr
Femara

Last edited by harrie; 02-27-2009 at 09:07 PM..
harrie is offline   Reply With Quote
Old 02-25-2009, 06:23 PM   #63
lizm100
Senior Member
 
lizm100's Avatar
 
Join Date: Mar 2008
Posts: 141
Maryanne-

I'm sooooo glad that your biopsy turned out to be B9!!!! It's incredible how our mind thinks the worst after having cancer, we've all been there. Things that we would have never paid attention to b/4, now we fear. In any case, you can rest assured and celebrate!!!

Wishing you the very best,
Liz
lizm100 is offline   Reply With Quote
Old 02-25-2009, 06:51 PM   #64
tricia keegan
Senior Member
 
tricia keegan's Avatar
 
Join Date: Nov 2005
Location: Ireland
Posts: 3,463
Maryanne, so glad you got a B9, I did too so we both have both have lots to feel grateful for!
__________________
Tricia
Dx July '05 IDC 1.9cm Triple positive 3/9 nodes positive
A/C X 4 ..Taxol/Herceptin x 12 wks then herceptin 1 yr
Rads x 36 ..oophorectomy August '06
Currently taking Arimidex..
June 2011 osteopenia/ zometa x1 yearly- stopped Zometa 2015 as Dexa show normal bone density.
Stopped Arimidex July 2014- Restarted Arimidex 2015 for a further two years on the advice of my Onc.
2014 Normal Dexa scan
2018 Mammo all clear, still NED!
tricia keegan is offline   Reply With Quote
Old 02-25-2009, 11:37 PM   #65
harrie
Senior Member
 
harrie's Avatar
 
Join Date: Mar 2007
Location: Hilo, Hawaii
Posts: 1,867
Yea Tricia!! Now we can both bring our shoulders back and down and take that nice deep exhale!!
__________________
*** MARYANNE *** aka HARRIECANARIE

1993: right side DCIS, lumpectomy, rads
1999: left side DCIS, lumpectomy, rads, tamoxifen

2006:
BRCA 2 positive
Stage I, invasive DCIS (6mm x 5mm)
Grade: intermediate
sentinal node biopsy: neg
HER2/neu amplified 4.7
ER+/PR+
TOPO II neg
Oncotype dx 20
Bilat mastectomy with DIEP flap reconstruction
oophorectomy

2007:
6 cycles TCH (taxotere, carboplatin, herceptin)
finished 1 yr herceptin 05/07
Arimidex, stopped after almost 1 yr
Femara
harrie is offline   Reply With Quote
Old 02-26-2009, 03:37 PM   #66
ElaineM
Senior Member
 
ElaineM's Avatar
 
Join Date: May 2006
Posts: 3,142
Wink Need your prayers

Regarding the Han Chinese and the Jews. There has been travel between the Middle East, various parts of Asia, Asia Minor (modern day Turkey), Africa and Europe since the earliest times, so the Jews who migrated from the Middle East to Western and Eastern Europe (Askauer - spelling ?? Jews) may not be the only ethnic group that can carry the BRCA genes. I learned in linguistics class that the old Turkish language is in the same language family as the old Chinese language. Humm. Interesting. I always thought that it might be possible for other ethnic groups to carry the BRCA genes.
__________________
Peace,
ElaineM
12 years and counting
http://her2support.org/vbulletin/showthread.php?t=48247
Lucky 13 !! I hope so !!!!!!
http://her2support.org/vbulletin/showthread.php?t=52807
14 Year Survivor
http://her2support.org/vbulletin/showthread.php?t=57053
"You never know how strong you are until being strong is the only choice you have." author unknown
Shared by a multiple myeloma survivor.
ElaineM is offline   Reply With Quote
Old 02-27-2009, 08:56 PM   #67
Unregistered
Guest
 
Posts: n/a
Harrie,Elaine et al,
My computer died for real this time...sigh...so for now on husbands laptop (ugh)...I would love to go into detail but that will have to wait except to say that there are literally hundreds of ethnic groups that have had specific BRCA mutation identified...

This might be of interest...
"the Portuguese converso connection may explain how the Jewish mutation got to Western India, but I now realize that Goa is long way from Konkan. But the Chitpavan home area there, isn't it the same place where the Bene Israel used to live before they moved to Mumbai and, ultimately, all the way to Israel?

Bene Israel have their claim to Jewish roots confirmed by modern genetic studies. Their maternal lineage (mitochondrial) is local Maharashtran, but the paternal lineage (Y-chromosome) is famous Jewish Kohanim. According to their legends they moved to India in 2nd century BCE. So there were some people with really old Jewish roots in your own ancestral neighborhood.

The only problem is, I couldn't find any references to 187delAG being found in any Bene Israel. If the mutation doesn't exist in their population, then it must have reached you by some other route..."
  Reply With Quote
Old 02-27-2009, 10:35 PM   #68
Adriana Mangus
Senior Member
 
Join Date: May 2006
Location: California
Posts: 668
Glad to hear good news

Harrie;

I'm happy for you. Thank God it was just a case of a "broken" back.

Love,

Adriana
__________________
1994 - rt brst, .lump, underarm node dissection,chemo+rad 1.2 cms, Grade 3.
28 nodes neg
Er,Pr, Positive HER2 status unknown
2003- Recur to rt lung.July 16 ( B-Day!)
Her2+++ Er,Pr, Negative
2003 - Aug04--Navelbine + Herceptin
2004- 2007--
NED - Herceptin, only
2007 Feb-April Xeloda added to hereceptin
2007-May Back on Navelbine+Herceptin
2008-Feb-Mar 15 Ses Rad to Rt. Lung
2008- Oc 17 Add Tykerb to Herceptin
2009- June-- Discont Tykerb
2009 July 7--Current Taxol + Herceptin
2009 Dec--Discontinued treatment due to progression. Looking into cyberknife.
2010-Aug Accepted to TDM1, no SE, except liver count went up.
2010-2011 September got kicked out of the trial, due to a small spot found on lung.
2011- 2012 September thru early 2013 on Herceptin
2013- March Bone density shows small spot on 5th rib.
2013 - April 4th appt with onc. will post after discussing course of treatment.
2013-March-April Cyber knife to brain and radiation to rib. Chest --base line before chemo-CT-Scan stable for lung issue. CA2729 Normal.
2013 April Herceptin- TDMI
2013 Sept Herceptin + Perjeta . CA2729 within normal range. Brain and Pet scans October 31st. will post results.
2013 October Brain MRI- mixed response. Will see Onc/rad on Halloween.
2013 October/November Brain-MRI nothing new. Repeat MRI next year in May.

2013 December Continue Herceptin and Perjeta. Stable at the moment.
2014 February Brain MRI -clear!
2014 January Added Taxotere to Perjeta+Herceptin.
2014 March Stopped chemo-chest ct-scan next.

2014- March Scans shows tumor's larger, CA2729 higher. Discontinue Herceptin.
2014 April Perjeta+ Halaven
2014 April CA2729 went down 60 points after one cycle. Cough does not want to go away.
2014 June Continue on Perjeta + Halaven-- no more cough. Stable
2014 June Back on Herceptin + abraxane
Adriana Mangus is offline   Reply With Quote
Old 02-28-2009, 10:56 AM   #69
ElaineM
Senior Member
 
ElaineM's Avatar
 
Join Date: May 2006
Posts: 3,142
Wink Need your prayers

Aloha unregistered guest and harrie,
There was vibrant trade, diplomatic and religious missions between Japan and the rest of the world all the way up to the early 17th century and then after the mid 1800's, so it is quite possible that travelers (including Askauer Jewish people) got to Japan from Goa, the rest of Asia, Europe, the Middle East, Africa and all of the Americas. Asians came to the Americas in rather large groups after the late 1800's. It is very possible that BRCA can be found in many ethnic groups in addition to the ones medical professionals have identified.
__________________
Peace,
ElaineM
12 years and counting
http://her2support.org/vbulletin/showthread.php?t=48247
Lucky 13 !! I hope so !!!!!!
http://her2support.org/vbulletin/showthread.php?t=52807
14 Year Survivor
http://her2support.org/vbulletin/showthread.php?t=57053
"You never know how strong you are until being strong is the only choice you have." author unknown
Shared by a multiple myeloma survivor.
ElaineM is offline   Reply With Quote
Old 03-01-2009, 08:25 AM   #70
Joan M
Senior Member
 
Joan M's Avatar
 
Join Date: Oct 2007
Posts: 1,851
Maryanne,

Great news. I'm so relieved to hear that the results were benign.

Joan
__________________
Diagnosed stage 2b in July 2003 (2.3 cm, HER2+, ER-/PR-, 7+ nodes). Treated with mastectomy (with immediate DIEP flap reconstruction), AC + T/Herceptin (off label). Cancer advanced to lung in Jan. 2007 (1 cm nodule). Started Herceptin every 3 weeks. Lung wedge resection April 2007. Cancer recurred in lung April 2008. RFA of lung in August 2008. 2nd annual brain MRI in Oct. 2008 discovered 2.6 cm cystic tumor in left frontal lobe. Craniotomy Oct. 2008 (ER-/PR-/HER2-) followed by targeted radiation (IMRT). Coughing up blood Feb. 2009. Thoractomy July 2009 to cut out fungal ball of common soil fungus (aspergillus) that grew in the RFA cavity (most likely inhaled while gardening). No cancer, only fungus. Removal of tiny melanoma from upper left arm, plus sentinel lymph node biopsy in Feb. 2016. Guardant Health liquid biopsy in Feb. 2016 showed mutations in 4 subtypes of TP53. Repeat of Guardant Health biopsy in Jana. 2021 showed 3 TP53 mutations, BRCA1 mutation and CHEK2 mutation. Invitae genetic testing showed negative for all of these. Living with MBC since 2007. Stopped Herceptin Hylecta (injection) treatment in March 2020. Recent 2021 annual CT of chest, abdomen and pelvis and annual brain MRI showed NED. Praying for NED forever!!
Joan M is offline   Reply With Quote
Reply

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

Forum Jump


All times are GMT -7. The time now is 01:35 PM.


Powered by vBulletin® Version 3.8.7
Copyright ©2000 - 2024, vBulletin Solutions, Inc.
Copyright HER2 Support Group 2007 - 2021
free webpage hit counter