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Breast Cancer Meeting Highlights News fro recent ASCO and San Antonio Meetings

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Old 12-05-2008, 08:05 AM   #1
Hopeful
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Determination of HER2 amplification - when should chromosome 17 also be determined

http://www.abstracts2view.com/sabcs/...u=SABCS08L_237

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Old 12-14-2008, 04:33 PM   #2
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Is it just me or does it seem equivocal FISH and this polysomy 17 issue is being bounced around with no clear recommendations?
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Old 12-14-2008, 05:55 PM   #3
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They probably need to understand the ramifications of this and possible studies to support what they might be looking for.

I am just commenting that Chromosome 17 is the chromosome BRCA 1 resides. There may be a familial link for those who are Her2+ and have polysomy 17 perhaps? (Just thinking out loud here).

PS - BRCA 2 resides on Chromosome 13
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Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
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Last edited by Becky; 12-14-2008 at 05:55 PM.. Reason: Add PS
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