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Old 11-12-2007, 08:09 AM   #1
betlen5
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Location: Suwanee, Georgia.
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Post Abraxane/Tykerb need advise

Can anyone give me some advise about the side effects of Abraxane? I start Abraxane/Tykerb today. Was on Tykerb/Xeloda for 9 months and cancer has returned for the 6th time. Considering going to Birmingham, Al for second opion on my treatment regimen since 01/2002.

Had pet scan on 11/9 and will also get the results today. Fearfull of cancer spreading to other orgins.

Thanks for your feedback!

Betty
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1/2002 DX stage IIa IDC er/pr+ her2 3+ positive: insitu ductal carcinoma right breast, 3cm 8 node removal all neg;lumpectomy;4 rounds A/C; 33 rads
tamoxifen
4/2004 DX Local Reacurrance; er/pr+ her2 3+ positive; nodes 9 of 12 positive largest 1.5 cm; 28 rads;stopped tamoxifen;went on Femara/lupron
8/2004 DX Local Reacurrance; er/pr+ her2 3+ positive; dbl mas reconstructive surgery w/tran flap; no chemo or drugs
11/2005 DX Local Reacurrance; er/pr+ her2 3+ positive; Taxol/Herceptin 1x weekly for 12 weeks; Herceptin for 9 months 1x 21 days
12/2006 DX Local Reacurrance; er/pr- her2 3+ positive; Her 2 rechecked with FISH her2+++ er/pr-
3/9/07 Started Tykerb (Lapatinib) 1250 mg/once daily
Xeloda (Capecitabine 2000 mg/m2/daily 1-14 every 21 days
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Old 11-12-2007, 02:49 PM   #2
Sheila
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Betty
Abraxane is supposed to be much easier on you than Taxol...I wanted Abraxane, but my insurance company wouldn't pay for it...only Taxol as it is so expensive. My friend was on it, did not lose her hair, although some do, and had no problems...the best is that there is no pre meds or steroids. You have been on the Tykerb, so you know what that is like...you might want to email Lolly as she was on Tykerb Abraxane...I went from Xeloda to Taxol....I wish I could get the Abraxane! I see your problem area is the Axilla...that is where Lolly's is....private message her, she is a doll! She was so much help to me!
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Sheila
Diagnosed at age 49.99999 2/21/2002 via Mammography (Calcifications)
Core Biopsy 2/22/02
L. Mastectomy 2/25/2002
Stage 1, 0.7cm IDC, Node Neg from 19 nodes Her2+++ ER PR Neg
6/2003 Reconstruction W/ Tissue Expander, Silicone Implant
9/2003 Stage IV with Mets to Supraclavicular nodes
9/2003 Began Herceptin every 3 weeks
3/2006 Xeloda 2500mg/Herceptin for recurrence to neck nodes
3/2007 Added back the Xeloda with Herceptin for continued mets to nodes
5/2007 Taken Off Xeloda, no longer working
6/14/07 Taxol/Herceptin/Avastin
3/26 - 5/28/08 Taxol Holiday Whopeeeeeeeee
5/29 2008 Back on Taxol w Herceptin q 2 weeks
4/2009 Progression on Taxol & Paralyzed L Vocal Cord from Nodes Pressing on Nerve
5/2009 Begin Rx with Navelbine/Herceptin
11/09 Progression on Navelbine
Fought for and started Tykerb/Herceptin...nodes are melting!!!!!
2/2010 Back to Avastin/Herceptin
5/2010 Switched to Metronomic Chemo with Herceptin...Cytoxan and Methotrexate
Pericardial Window Surgery to Drain Pericardial Effusion
7/2010 Back to walking a mile a day...YEAH!!!!
9/2010 Nodes are back with a vengence in neck
Qualified for TDM-1 EAP
10/6/10 Begin my miracle drug, TDM-1
Mixed response, shrinking internal nodes, progression skin mets after 3 treatments
12/6/10 Started Halaven (Eribulen) /Herceptin excellent results in 2 treatments
2/2011 I CELEBRATE my 9 YEAR MARK!!!!!!!!!!!!!
7/5/11 begin Gemzar /Herceptin for node progression
2/8/2012 Gemzar stopped, Continue Herceptin
2/20/2012 Begin Tomo Radiation to Neck Nodes
2/21/2012 I CELEBRATE 10 YEARS
5/12/2012 BeganTaxotere/ Herceptin is my next miracle for new node progression
6/28/12 Stopped Taxotere due to pregression, Started Perjeta/Herceptin

Last edited by Sheila; 11-12-2007 at 02:51 PM..
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