Go Back   HER2 Support Group Forums > Articles of Interest
Register Gallery FAQ Members List Calendar Search Today's Posts Mark Forums Read

Thread Tools Display Modes
Old 07-20-2010, 06:34 AM   #1
Senior Member
Join Date: Aug 2006
Posts: 3,379
Neoadjuvant Femara study highlights heterogeneity of response to AI

Provocative results:

"Gene expression changes after 14 days’ treatment with letrozole revealed different patterns of change in oestrogen regulated and proliferation genes in individual resistant tumours. Tumours could be separated into 3 different subgroups as follows: i) 9 cases in which both proliferation and oestrogen signalling signatures were generally reduced on treatment (ii) 4 cases in which both signatures were generally unaffected or increased with treatment and (iii) 2 cases in which expression of the majority of oestrogen-regulated genes decreased whereas proliferation genes remained unchanged or increased."

Hopeful is offline   Reply With Quote

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is On

Forum Jump

All times are GMT -7. The time now is 11:38 PM.

Powered by vBulletin® Version 3.8.7
Copyright ©2000 - 2019, vBulletin Solutions, Inc.
Copyright HER2 Support Group 2007
free webpage hit counter