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Old 08-25-2008, 02:00 PM   #1
Brenda S
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How long is recommended for herceptin?

I have just had my last Taxotere/Carboplatin/Herceptin infusion. I've had six treatments--one every third week. I have now to finish with herceptin alone for 12 more treatmets. That will be a full year of Herceptin. I've experienced some rather nasty side-effects, fatigue, extreme constipation, intermittent nausea and generally feeling lousy for about a week after each infusion. But I'm now over the worst I hope. My question is: What is the optimum time to be on herceptin? I've heard everything from six months to three years. Are there any definitive studies I can look at? Any help is appreciated.
Thanks!
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Diagnosed 3/08 at age 57
1.1cm tumor, ER-PR-, Her2 3+(rt side)

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Node negative
clean margins
Stage 1
lumpectomy 4/08
Mammocite Radiation 4/08
Will begin TCH Chemo 5/08
TCH 3 week cycle for 6 cycles
Herceptin alone for 18 more treatments on a 3 week cycle
Total chemo 12 months
Neulasta 24 hours after each cycle
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Old 08-25-2008, 03:36 PM   #2
Brenda_D
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My Onc said 1 year is the standard. I would think optimum would vary with the person being treated?
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Old 08-25-2008, 05:44 PM   #3
Joe
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Brenda,

There were no differences in the BIRG study - one year of Herceptin and the European HERA study - 2 years of Herceptin.

Many of those that reoccured in both studies went back into remission after Herceptin was continued.

Regards
Joe
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