Researchers Find Gene Signature Predictive of Late Distant Recurrence

[malik125]

after initial treatment) was associated with mesenchymal characteristics of the tumor epithelium and gene expression alterations in the adjacent tumor stroma. Though occurrence
of late disease recurrence could be affected by genetic alterations acquired during the long latency of a dormant stage, the existence of a predictive gene signature for late recurrence in the primary tumor suggests that intrinsic features of this tumor govern the transition of disseminated tumor cells into a dor

Mohsin