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Old 08-02-2007, 07:56 AM   #1
MCS
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Question Aranesp

A question regarding use.

I used aranesp after every chemo treatment to manage my wbc. And it worked wonders.

The current studies of it are suggesting not to use it and even the Neulasta as well.

What are your doctors opinions on this.

I believe that it's such a good drug when given at the right time. I know it helped me with my counts.

thank you

Maria
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Old 08-02-2007, 06:13 PM   #2
Lolly
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Hi Marie,
I had Aranesp during one of my 6 month regimen's with Navelbine when my Hemoglobin dropped below 9. My onc is very cautious with it, and I only got an injection every other week, and I was told it my HGB came up to 12 he would stop the Aranesp as the danger is in continuing it in the presence of normal counts. At least that's my understanding.

I only had to have Neulasta once, but I know there are several others here who had to receive regular injections of both white and red cell boosters in order to get through treatment.

I think caution is the key word with these drugs, but when they're needed in order to stay on schedule with treatment, they are warranted.
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Sept.'99 - Dx.Stage IIIB, IDC ER/PR-, HER2+++ by IHC, confirmed '04 by FISH. Left MRM, AC x's 4, Taxol x's 4, 33 Rads, finishing Tx May 2000. Jan.'01 - local/regional recurrence, Stage IV. Herceptin/Navelbine weekly till NED August 2001, then maintenance Herceptin. Right Mast. April 2002. Local/Regional recurrence April '04, Herceptin plus/minus chemo until May '07. Gemzar added from Feb.'07-April '07; Tykerb/Abraxane until August '07, back on Herceptin plus Taxotere and Xeloda Sept. '07. Stopped T/X Nov. '07, stopped Herceptin Dec. '07, started Avastin/Taxol/Carboplatin Dec. '07. Progression in chest skin, stopped TAC March '03, started radiation.

Herceptin has served as the "Backbone" of my treatment strategy for over 6 years, giving me great quality of life. In 2005, I was privileged to participate in the University of Washington/Seattle HER2 Vaccine Trial.
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Old 08-02-2007, 08:13 PM   #3
jhandley
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Smile wbc

Hi
i use reishi mushroom extract (Greenridge Immune support)..a few sips a day stopping a couple of days before chemo and waiting 2 days after.

Great for boosting wbc and some research shows it helps things like herceptin work better.
Jackie
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Old 08-03-2007, 12:09 PM   #4
TSund
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aranesp

How low during chemo should RBC go before getting treatment?

THX

TRS
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Terri, spouse of Ruth, Dallas/Ft. Worth area
Ruth dx 05/01/07 (age 50) Filipino
multifocal, several tumors .5 -2.5 cm, large area
Breast MRI showed 2 enlarged nodes, not palpable
100%ER+, 95%PR+, HER2+++
6x pre-surgery TCH chemo finished 9/15/7 Dramatic tumor shrinkage
1 year Herceptin till 6/08
MRM 10/11/07, SNB: 0/4 nodes + Path: tumors reduced to only a few "scattered cells"
now 50% ER+, PR- ???
Rads finished 1/16/08
Added Tamoxifen,
Finished Herceptin 05/08
NOW is the time to appreciate life to the fullest.
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Old 08-03-2007, 03:12 PM   #5
Barbara
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Blood Cell Stimulants

Hi:

I was surpised that there was a concern regarding both white cell stimulants such as Nuelasta and red cell stimulants (Arnesap, Procrit). I read two of the studies andy they only noted that red cell stimulants have been associated with faster cancer progression when comparing patients with or without red cell stimulants.

Barbara
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Old 08-03-2007, 08:49 PM   #6
Grace
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Here is Procrit's site, which then sends you to FDA site on these types of drugs. This is not a suggestion to anyone, just information to help you make your decision:

http://www.procrit.com/PHA.pdf#zoom=100
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