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Old 01-15-2010, 03:50 PM   #1
curryalso
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Cmf

Has anyone been treated with CMF and herceptin? I had severe reactions to TCH and was switched to CMF. Don't know anyone who is on this now. It used to be used quite often, but not anymore. Just wish I knew someone who had it with a good outcome.
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Old 01-15-2010, 05:11 PM   #2
ammebarb
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Re: Cmf

Hi curryalso. I write to the group because my sis was diagnosed as HER2 positive last March, however I am also a breast cancer survivor of twenty six years. HER2 wasn't tested for then, so I don't know my HER status, but I'm guessing I was not positive. I received a year of CMF chemo on a three week cycle, after a month of weekly treatments. My cancer was at least stage two, as I had nodes affected and a rather large tumor. I had a mastectomy, followed by the chemo. I remain vigilant about breast health, but have been NED since my surgery and treatment. I hope that you have good result with this regimen---it has certainly served me well! Perhaps a HER2 sister who has received this chemo will check in. Wishing you the very best!

Barb A.
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Old 01-15-2010, 08:48 PM   #3
Becky
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Re: Cmf

Dear Curry

You should privately message Juanita. She had CMF with Herceptin and she is over 5 yrs out and doing great.
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Becky

Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia

NED 18 years!

Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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Old 01-15-2010, 08:50 PM   #4
Rich66
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Re: Cmf

More on the C part here:
http://her2support.org/vbulletin/showthread.php?t=43357

A lot of the metronomic studies are done with oral Cyclophoshamide (C). Some combine it with Capecitabine (an oral version of F).
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Mom's treatment history (link)
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Old 01-21-2010, 01:10 PM   #5
curryalso
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Re: Cmf

Thanks for responding. I'm glad to hear someone had good results.
So few people are on CMF so it's hard to talk to anyone. I appreciate your response I'm on a 3 week cycle with Herceptin. Hoping for the best.
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Old 01-21-2010, 01:10 PM   #6
curryalso
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Re: Cmf

How do I get in touch with Juanita?
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Old 01-21-2010, 01:39 PM   #7
curryalso
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Re: Cmf

Thanks for the info
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Old 01-22-2010, 09:45 AM   #8
juanita
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Re: Cmf

hey just saw this thread. not on as much as i used to be. i did 6 treatments of cmf and then a year of herceptin because that was when it was finally released to everyone. i tolerated the cmf very well. had just a little nausea with the last treatment. in september i marked my 5 yr cancerversary. if you have any questions ask away! i'll be glad to answer them for you.
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dxd 9-04, lumpectomy,
st 1, gr 3, er,pr-, her2 +,
2 tac,33 rads,6 cmf
1 yr herceptin,
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Old 01-22-2010, 01:16 PM   #9
curryalso
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Re: Cmf

Hi, Thanks for answering. I had a mastectomy in July and restructure at the same time. I started on TCH but had an allergic reaction. I'm now on CMF C (orally) and i seem to be tolerating it well.

Herceptin will be for one year I also am ER/PR - and her2+.

Was just a little scared that this was not an effective treatment and that the TCH was better. I actually feel pretty good and was thinking that the chemo could not be working if I felt pretty good.

Just looking for some positives, and thank you for letting me know that you are celebrating 5 yrs. I was 64 when I was diagnosed.
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Old 01-22-2010, 09:18 PM   #10
juanita
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Re: Cmf

i was 41 when diagnosed. had 2 tac first and was very violently ill even with anti nausea meds so stopped that then did radiation and then did the 6 cmf. i'm also er/pr - and was a stage 1. good luck!
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dxd 9-04, lumpectomy,
st 1, gr 3, er,pr-, her2 +,
2 tac,33 rads,6 cmf
1 yr herceptin,
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