Re: How Her2+ BC patients develop brain metastases
I will have to get a closer look at the work they have done with this, to see whether they are talking about detecting the reelin protein solely by actual tissue sampling, or whether there is a current form of imaging that can detect it.
I'm still receiving annual breast MRI's and annual mammograms (alternating 6 months apart), although I haven't had an onc since 2006. (I never did any trastuzumab, and chose to discontinue tamoxifen fairly early on.)
I had a definite memory deficit this spring that was concerning, but with no physical evidence to support anything but doing serial mini-mental exams for future comparisons, I had to use a pick, hammer and shovel to get any brain imaging done. A noncontrast brain MRI showed nothing. Which is what it would show if noncontrast brain imaging doesn't detect the reelin.
A.A.
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Dx 2002 age 51
bc for granny, aunt, cousin, sister, mother.
ER+/PR+/HER2+++, grade 3
IDC 1.9 cm, some DCIS, Stage 1, Grade 3
Lumpectomy, CAFx6 (no blood boosters), IMRT rads, 1 3/4 yr tamoxifen
Rads necrosis
BRCA 1 & 2 negative
Trials: Early detection OVCA; 2004 low-dose testosterone for bc survivors
Diet: Primarily vegetarian organic; metformin (no diabetes), vitamin D3
Exercise: 7 days a week, 1 hr/day
No trastuzumab, no taxane, no AI
NED
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