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08-31-2011, 07:27 AM
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#1
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Senior Member
Join Date: May 2010
Location: Elizabethton, TN
Posts: 418
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PET Scan
Does anyone have knowledge re "SUV" numbers on PET scan results. I had my first scan last week and had a "max SUV 3.3 on C7" (cervical vertabrae). Also had "max SUV 3.4 liver". I've done lots of searches online (probably a bad idea) and some sites indicate an SUV over 2.5 indicates malignancy - others say any inflammation, arthritis, infection can cause the elevated numbers. Waiting for results from a follow-up MRI that was done this morning to get final call from my onc? The waiting is so terrifying (as you all know) so I thought I'd check with others here. Thanks for any help.
__________________
Joni -64 yrs old -
3/01/10: found lump in rt.breast
3/12/10: mammogram/ultrasnd/biopsy-invasive bc & DCIS; 2 tumors (2cm er-/pr-/HER2-& 1.8 cm er-/pr-/HER2+); grade 3;poorly differentiated
3/24/10:sent.node biopsy clear
3/31/10:bi-lateral mx.;atypical ductal hyperplasia-lft side
4/21/10:wound revision-infection/scarring 4/28/10:seromas both sides
5/21/10:port installed,TCH chemo (6 x 3 wks); Herc,-1yr; 33 rad tx after chemo
07/2010: port not working-2nd port didnt'work;3rd port opposite side.
07/2010: 2 weeks after 3rd port surgery, threw 3 pulm. emboli-IVC filter installed; warfarin
08/2010: hospitalizations w/3 of chemos; decision to stop after 4th-on to radiation in Oct 2010;Herc cont.
12/03/2010 - finished 33 rads Hooray!! cont. Herc. every 3 wks
4/2011 - pneumonia ??? Nope-radiation pneumonitis. No more Herc.
5/2011 - NED!!! port out.
8/2011 - clean PET & CT scans.Still NED
7/2012 - Still NED/very blessed.
2/2013 - 6 mos checkup-all clear. CA2729 down frm 13 to 11.
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08-31-2011, 10:07 AM
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#2
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Senior Member
Join Date: May 2006
Posts: 3,142
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Re: PET Scan
SUV indicates the amount of the radioactive glucose solution found by the scanner in each area of concern.
If there is cancer in the areas of concern it is probably small since the SUV amount was small. SUV numbers can be much higher. Also tumors have to be at least 5 or 6 cm to show up on a pet scan.
I hope this explanation helps. Take care.
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08-31-2011, 12:44 PM
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#3
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Senior Member
Join Date: Jan 2008
Location: "Love never fails."
Posts: 5,808
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Re: PET Scan
The article in the link below is about PET in lung cancer. But I thought the information about SUV and tumor size might be relavent here:
http://theoncologist.alphamedpress.o...t/9/6/633.full
__________________
Jackie07
http://www.kevinmd.com/blog/2011/06/doctors-letter-patient-newly-diagnosed-cancer.html
http://www.asco.org/ASCOv2/MultiMedi...=114&trackID=2
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08-31-2011, 08:25 PM
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#4
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Senior Member
Join Date: Jul 2011
Location: Melbourne, Australia
Posts: 432
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Re: PET Scan
I'm sorry Joni but I don't know the answer to your question. I wanted to ask Elaine though about her saying,
Quote:
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Also tumors have to be at least 5 or 6 cm to show up on a pet scan.
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I don't know if this is true as the PET that I had detected my numerous lung mets - the largest of which was 8mm and an axilla node that was 2.1cm. It had trouble detecting my skin met significantly which was about 2.5 x 2cm. I am just wondering where the information that a tumor has to be 5-6cm to be detected came from? The dimensions of the tumors have been confirmed with CT.
I wish you the best with getting some answers Joni.
__________________
Amanda xx
40 year old Mum to three gorgeous kids - son 5 and daughters 8 and 11
Wife to my wonderfully supportive husband of 17 years!
22 February 2011 - Diagnosed Early Breast Cancer IDBC Stage2b (ER/PR -ve, Her2+ve +++) - 38 years old
(L) skin sparing mastectomy with tissue expander, axilla clearance (2/14 affected) clear margins.
Fec*3, Taxotere and herceptin*2 - stopped due to secondary diagnosis
June 24 2011 Stage IV - Skin met, axilla node, multiple lung lesions
Bolero3 trial - Navelbine, Hereptin weekly, daily Everolimus/Placebo
February 2012 - July 2012 Tykerb and Xeloda - skin mets resolved, Lungs initially dramatically reduced but growing again
August 2012 (turn 40!) tykerb and herceptin (denied compassionate use of TDM1) while holidaying in Italy!
September 2012 - January 2013 TDM1 as part of the Th3resa trial - lymph nodes resolved, lungs slowly progressing.
January 2013 - herceptin, carboplatin and Perjeta (compassionate access)
April 2013 - Some progression in lungs and lymph nodes - Abraxane, Herceptin and Perjeta
July 2013 - mixed response - dramatic reduction of most lung disease, progression of smaller lung nodules and cervical and hilar nodes - ? Add avastin.
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08-31-2011, 09:03 PM
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#5
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Senior Member
Join Date: May 2006
Posts: 3,142
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Re: PET Scan
Amanda,
I got the information about size from the most experienced and senior pet/ct scan technician at the hospital where I go for my tests. I am very curious and often ask medical professionals questions about whatever is going on at the moment. I have learned alot and continue to learn alot everyday.
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08-31-2011, 09:33 PM
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#6
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Senior Member
Join Date: Jul 2011
Location: Melbourne, Australia
Posts: 432
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Re: PET Scan
Thanks Elaine - It is interesting isn't it? Mine definitely showed on PET and were confirmed on CT. Maybe they cannot accurately measure them on PET under 5-6cm?
I then had a bone scan show some warm spots - nothing on PET so it was assumed they were a result of changes in bone from chemo not mets. My onc was saying that they frequently get differences in results depending upon the scan methods.
we are learning all the time aren't we?
__________________
Amanda xx
40 year old Mum to three gorgeous kids - son 5 and daughters 8 and 11
Wife to my wonderfully supportive husband of 17 years!
22 February 2011 - Diagnosed Early Breast Cancer IDBC Stage2b (ER/PR -ve, Her2+ve +++) - 38 years old
(L) skin sparing mastectomy with tissue expander, axilla clearance (2/14 affected) clear margins.
Fec*3, Taxotere and herceptin*2 - stopped due to secondary diagnosis
June 24 2011 Stage IV - Skin met, axilla node, multiple lung lesions
Bolero3 trial - Navelbine, Hereptin weekly, daily Everolimus/Placebo
February 2012 - July 2012 Tykerb and Xeloda - skin mets resolved, Lungs initially dramatically reduced but growing again
August 2012 (turn 40!) tykerb and herceptin (denied compassionate use of TDM1) while holidaying in Italy!
September 2012 - January 2013 TDM1 as part of the Th3resa trial - lymph nodes resolved, lungs slowly progressing.
January 2013 - herceptin, carboplatin and Perjeta (compassionate access)
April 2013 - Some progression in lungs and lymph nodes - Abraxane, Herceptin and Perjeta
July 2013 - mixed response - dramatic reduction of most lung disease, progression of smaller lung nodules and cervical and hilar nodes - ? Add avastin.
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09-01-2011, 06:35 AM
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#7
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Senior Member
Join Date: May 2010
Location: Elizabethton, TN
Posts: 418
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Re: PET Scan
Thanks ladies - maybe the size thing is as simple as 5-6 "mm" not "cm"???? I know my report showed some things that small (areas of inflammation-probably arthritis). I did talk to a nurse at my onc center and she was more reasurring yesterday that there was probably not any malignancies - just the inflammation type stuff. I think it's important for patients to always get copies of reports but also it's really hard not to freak about on the things we don't totally understand or the overall impact of the radiologist's wording. I'm still waiting on the MRI results which should be sometime this morning. If I haven't heard by lunchtime today, Robin told me she would call and get the report for me by phone so I won't have to spend the holiday weekend worrying.
__________________
Joni -64 yrs old -
3/01/10: found lump in rt.breast
3/12/10: mammogram/ultrasnd/biopsy-invasive bc & DCIS; 2 tumors (2cm er-/pr-/HER2-& 1.8 cm er-/pr-/HER2+); grade 3;poorly differentiated
3/24/10:sent.node biopsy clear
3/31/10:bi-lateral mx.;atypical ductal hyperplasia-lft side
4/21/10:wound revision-infection/scarring 4/28/10:seromas both sides
5/21/10:port installed,TCH chemo (6 x 3 wks); Herc,-1yr; 33 rad tx after chemo
07/2010: port not working-2nd port didnt'work;3rd port opposite side.
07/2010: 2 weeks after 3rd port surgery, threw 3 pulm. emboli-IVC filter installed; warfarin
08/2010: hospitalizations w/3 of chemos; decision to stop after 4th-on to radiation in Oct 2010;Herc cont.
12/03/2010 - finished 33 rads Hooray!! cont. Herc. every 3 wks
4/2011 - pneumonia ??? Nope-radiation pneumonitis. No more Herc.
5/2011 - NED!!! port out.
8/2011 - clean PET & CT scans.Still NED
7/2012 - Still NED/very blessed.
2/2013 - 6 mos checkup-all clear. CA2729 down frm 13 to 11.
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09-01-2011, 05:54 PM
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#8
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Senior Member
Join Date: Apr 2010
Posts: 129
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Re: PET Scan
A lot of PET/CT's won't show anything smaller than 1cm, but the higher resolution ones show very tiny ones. Some of my lung nodules were 4mm when they lit up on high resolution PET/CT. My guess is that the tech meant mm not cm.
Good luck with the MRI results. I hope shows no mets!
__________________
March 2010: Diagnosed with Stage IIIC IDC with axillary, mammary and suplaclavicular node involvement. ER/PR -, HER2+++. 7cm tumor in right breast.
April 2010: Started neoadjuvent chemo. 4 DD A/C every 2 weeks, 4 DD Taxotere every 3 weeks with Herceptin weekly.
August 2010: Finished chemo!
August 20, 2010: PET/CT showed no cancer in any nodes, and only a little uptake to the breast.
September 9, 2010: Bilateral mastectomy with immediate reconstruction with implants and Alloderm.
September 16, 2010: Pathology report showed 18/51 positive axillary nodes, 3.2cm tumor. Granual sized cancer found in the fatty tissue between levels 1 and 2.
October 19, 2010: CT showed several spots on lungs and 1 spot on liver. Liver spot is 2mm, lung spots range from 2mm to 4mm. We don't know if they are cancer or not.
12/15/10: Brain MRI clear
1/7/11: PET/CT
1/13/11: Recurrence in lungs. Start Tykerb
5/13/11: Progression in lungs
6/3/11: Lung surgery to get tumors for chemosensitivity testing.
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09-01-2011, 06:05 PM
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#9
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Senior Member
Join Date: May 2010
Location: Elizabethton, TN
Posts: 418
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Re: PET Scan
Blessed yet again! MRI was ok - uptake was from arthritic changes and inflammation. Showed several bone spurs and the C7 vertabra is pretty much grinding on other bone but the nurse asked again "Don't you have a lot of back and neck pain" ....I'm happy to say that I don't and even happier that there are no mets. Tonight I will breathe and sleep easy again. Thanks for the help and concern.
__________________
Joni -64 yrs old -
3/01/10: found lump in rt.breast
3/12/10: mammogram/ultrasnd/biopsy-invasive bc & DCIS; 2 tumors (2cm er-/pr-/HER2-& 1.8 cm er-/pr-/HER2+); grade 3;poorly differentiated
3/24/10:sent.node biopsy clear
3/31/10:bi-lateral mx.;atypical ductal hyperplasia-lft side
4/21/10:wound revision-infection/scarring 4/28/10:seromas both sides
5/21/10:port installed,TCH chemo (6 x 3 wks); Herc,-1yr; 33 rad tx after chemo
07/2010: port not working-2nd port didnt'work;3rd port opposite side.
07/2010: 2 weeks after 3rd port surgery, threw 3 pulm. emboli-IVC filter installed; warfarin
08/2010: hospitalizations w/3 of chemos; decision to stop after 4th-on to radiation in Oct 2010;Herc cont.
12/03/2010 - finished 33 rads Hooray!! cont. Herc. every 3 wks
4/2011 - pneumonia ??? Nope-radiation pneumonitis. No more Herc.
5/2011 - NED!!! port out.
8/2011 - clean PET & CT scans.Still NED
7/2012 - Still NED/very blessed.
2/2013 - 6 mos checkup-all clear. CA2729 down frm 13 to 11.
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