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04-29-2008, 03:38 PM
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#1
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Senior Member
Join Date: Nov 2005
Location: Lincoln, Rhode Island
Posts: 371
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My new treatment plan
I will be starting Xeloda Ixempra and Herceptin tomorrow. Please I need all your prayers that this will work. Thanks for everything I love you all. And any info will be apprciated on how this treatment has or is working for anyone.
All my Love
Karen
__________________
Love and Hope
Karen
IDC
DX 1998 STAGE I ER+/ PR+
AC CHEMO TILL FEB 1999
Tamxofin till 2001
2001 exstensive liver mets and mets to lungs
Started weekly taxol
Jan 2002 found out I was strongly HER2POS+++ started herceptin continued with taxol and herceptin till June 2002 then from June 2002 till Jan 2005 just herceptin and Arimidex
2005 Navelbine herceptin had RFA Then back on taxol with herceptin
April 2006 progression again went on clinical trial with tykrerb/herceptin progressed on the started Xeloda/ herceptin
Feb 2007 started Doxil
August 2007 Taxotere,Carboplatin and Herceptin exstensive mets to liver and pancreas
October 2007 Had to stop Carboplatin due to sever allergic reaction
Jan 2008
Stopped Taxotere due to progression now on Gemzar and Herceptin
March 2008 Starting Carboplatin, Abraxane, and Herceptin.
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04-29-2008, 03:53 PM
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#2
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Senior Member
Join Date: Sep 2006
Location: East Central Illinois
Posts: 89
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Karen, hope having a treatment plan in order helps you to feel better about the situation. I started on ixempra today. I am still rather loopy feeling from the premeds and am wondering how I will feel in the next few days. I was on the xeloda/tykerb combo for almost 11 months. I had side effects, but did well on the combo. Several gals on this site are on ixempra, so you might learn some about it from them. Yes, I am praying for you and I know many other sisters (and brothers) here are too. I also need prayers that this will work for me, so I would appreciate prayer for me too. Dear Karen we are thinking and cheering for you.
Becca
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04-29-2008, 04:03 PM
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#3
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Senior Member
Join Date: Jun 2006
Location: San Antonio, TX
Posts: 2,357
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Becca & Karen... if tons of prayer will make that stuff work better, it's a cinch! I'm adding my prayers for you both for fast, fantastic results. You are loved, ma
__________________
MA in TX.
Grateful for each and every day....
Diag. 12/05 at age 60
Stage II, Grade 3, 4.5 cm primary tumor
ER/PR- Her2 +3 strongly positive
Her2 by FISH 7.7 amplified
vascular invasion
Ki67 20% borderline
Jan - March '06 Taxotere/Adriamycin X 3 to try to shrink tumor - it grew
April '06 Rt Modified Radical Mas, 7 of 9 nodes positive
April - Aug. '06 Herceptin/Taxol/Carboplatin X 8 (dose dense)
Sept - Dec. '06 Navelbine/Herceptin x 8 (dose dense)
Radiation & Herceptin Jan. 22 - March 1, 2007
Finished Herceptin Dec. 10 '08! One extra year.
Port removed August, 2012.
8 1/2 years since diagnosis! 5 1/2 Years NED!
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04-29-2008, 04:03 PM
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#4
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Senior Member
Join Date: Nov 2007
Location: Connecticut
Posts: 2,077
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Sweetheart Karen, I'm glad you have a new plan ahead of you. I think Lopsided was/is on Ixempra and has had good results ( I think it was her), and I know with the Xeloda, in pill form, the dosage can be adjusted if you do have side effects. I think they usually do 2 weeks on, 1 off, and if you do have the "typical" Xeloda side effects- hand and foot syndrome, diarrhea, let your doc. know right away. I think you have a great combo. Thoughts and prayers for you, sweetie! Love, Bill
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04-29-2008, 04:24 PM
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#5
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Senior Member
Join Date: Aug 2006
Location: Sheboygan, WI
Posts: 2,582
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Dear Karen and Becca....
I ask God to bless you both with successful treatments. May your bodies be protected from the awful side effects these drugs can sometimes give us but may the drugs do what they are suppose to do for you. Also, I ask God to wrap His arms around you both and give you strength and peace.
My love and gentle hugs to you both....
Mary Jo
__________________
"Be still and know that I am God." Psalm 46:10
Dx. 6/24/05 age 45 Right Breast IDC ER/PR. Neg., - Her2+++ RB Mast. - 7/28/05 - 4 cm. tumor Margins clear - 1 microscopic cell 1 sent. node No Vasucular Invasion 4 DD A/C - 4 DD Taxol & Herceptin 1 full year of Herceptin received every 3 weeks 28 rads prophylactic Mast. 3/2/06
17 Years NED
<>< Romans 8:28
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04-29-2008, 04:34 PM
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#6
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Senior Member
Join Date: Sep 2005
Posts: 77
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Karen,
I've not had this treatment but you are most certainly in my prayers that this will work well. Take care and God Bless.
Carol
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04-29-2008, 05:17 PM
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#7
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Senior Member
Join Date: Sep 2005
Posts: 232
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I am praying for both of you, Karen and Becca. I know that a couple of people have had great success with the drug Ixempra, so I a certain that it will work for the two of you, too.
Sending love, strength and prayers you way.
Karen
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04-29-2008, 05:27 PM
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#8
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Senior Member
Join Date: Nov 2004
Posts: 190
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I'm praying for you Karen!!!!!!!!
__________________
8/98 dx right breast
5/2003 tram flap right breast
8/2004 dx new primary left breast with inflammatory bc
er/pr-, her2neu+++
8/19 taxotere and herceptin
1/15/2005 Navelbine/Herceptin
4/2005 radiation and Herceptin
5/15/2005 Herceptin alone
2/12/2008 skin biopsy positive
2/14/2008 met to sternum, possibly right breast
2/27/08 Start omitarg, herceptin, taxotere trial
3/17/08 Kicked off trial because I started too close to my last herceptin
3/19 start tykerb xeloda
Right breast confirmed met
5/15/08 skin mets gone, no hypermetabolic activity in breast, sternum healing
8/24/08 scans still look good. sternum still active with scarring. No evidence of progression
10/08 Progression in sternum
12/08 Start TDM1 trial
1/09 Scans show stable
12/09 1 year on TDM1 still stable
10/10 progression in chest and liver
11/10 false positive of liver mets; tykerb and herceptin
4/11 Tykerb/Herceptin/Xgeva
4/11 Rads to Sternum
5/12/12 NED Herceptin/Zometa
3/16/19 still NED Herceptin/Zometa very 6months
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04-29-2008, 05:40 PM
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#9
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Senior Member
Join Date: Sep 2005
Location: Stockton, NJ
Posts: 4,179
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You are in my thoughts that the new combo will kick cancer out the door.
__________________
Kind regards
Becky
Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia
NED 18 years!
Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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04-29-2008, 05:51 PM
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#10
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Senior Member
Join Date: Jul 2007
Location: Northern California
Posts: 764
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Karen,
I am praying that this new treatment works wonders for you. I think of you often.
Hugs,
Tonya
__________________
DX 02/01/07
2.5 cm, Er/Pr-, Her2+++
18/20 Nodes
03/07 CT & Bone scan - Clear
AC x 4, Taxol x 4, Added Herceptin
Radiation until 09/07
Herceptin every 3 weeks until 06/08
01/10/08 local recurrence -IBC
01/28/08 CT & Brain MRI - clear
02/08 - Navelbine & Herceptin
05/08 -MRM
05/08 - Gemzar & Herceptin - didn't work
09/08 - Hyperthermia rads
03/09 - Tykerb/Xeloda
05/10 - Tram flap to fix wound
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04-29-2008, 09:29 PM
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#11
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Senior Member
Join Date: May 2006
Posts: 157
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Karen and Becca
I am praying that this new combo will work great for both of you.
Hugs,
KarlaV.
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04-30-2008, 01:13 PM
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#12
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Senior Member
Join Date: Oct 2006
Location: Louisville KY
Naples FL
Posts: 665
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My prayers are with you that this new treatment will work. Sending healing thoughts your way.
patb
__________________
patb
Diagnosed June, 06, Stage I, Grade3, ER+PR- Her2positive, No Nodes. A/C X 4. Radiation 33 with boost, Herceptin every two weeks until Nov.
07, Arimedex for 5 years. Mugas and Echo and chest xRay. Bone scan of whole Body, and Back of Brain and spine MRI.
CT scan of Lungs every six months
due to two small places. December
2009, bone scan due to bone pain.
Follow up test in 2010.
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04-30-2008, 02:32 PM
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#13
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Senior Member
Join Date: Sep 2005
Location: Central Coast, CA
Posts: 3,207
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Karen, my heart - and prayers - go out to you. You are sure having a time of it trying to find the right mix. Ixempra seems like a good choice, as it is quite "different" from anything else you have tried. I hope and pray this one gives you the much needed relief you deserve.
You are always in my prayers.
__________________
Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial
5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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04-30-2008, 02:41 PM
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#14
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Senior Member
Join Date: Sep 2005
Posts: 556
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Dear Karen,
I am hoping and praying that this treatment will be the right thing for you.
Julie
__________________
Diagnosed in Sept 2004 while pregnant with the second child. Stage 3b, tumor 4.5cm, 4 auxillary and supraclav node positive. Her2+++ FISH 9.4 and er-,pr-.
Had dose dense neoadjuvant AC,Taxol then mastectomy,radiation+xeloda+Herceptin.
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04-30-2008, 05:01 PM
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#15
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Senior Member
Join Date: Apr 2006
Location: FLORIDA
Posts: 148
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Karen & Becca
Ixempra Was Good To Me And I Hope You Find It Tolerable. My Doctor Says He Loves Ixempra. He Told Me He Had Another Patient Who Was Very Sick & Basically Stayed In Bed Most Of The Time, He Put Her On Ixempra And She Is Up And Around And Feeling Much Better. Good Luck To Both Of You.
__________________
SHEILA (45)
09/2005--BREAST CANCER/8 POS NODES --A/C, MASTECTOMY,TAXOTERE, RADS, TAMOXIFEN,HERCEPTIN
02/2007--B/C METS TO OVARIES--HYSTERECTOMY, FASLODEX
12/2007--ENLARGING LYMPH NODES IN ABDOMEN--IXEMPRA, THEN TYKERB
08/2008--COLON TUMOR--A/C AGAIN,
12/2008--ABDOMEN TUMOR--AVASTIN/NAVELBINE FEMARA
05/2009--MET TO SPINE (L2) RADS
CURRENT TREATMENT
07/2009- START ZOMETA MONTHLY, XELODA & ABRAXANE......SURVIVING THE BEST I CAN
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04-30-2008, 05:30 PM
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#16
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Senior Member
Join Date: Jun 2006
Location: Bradenton,FL
Posts: 977
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Karen,
I so hope Ixempra does the trick! Thinking of you,
Marcia
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04-30-2008, 05:52 PM
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#17
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Senior Member
Join Date: Oct 2007
Posts: 1,851
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Karen,
I hope your first treatment went well, and that this is the answer you need. You're in my prayers.
Joan
__________________
Diagnosed stage 2b in July 2003 (2.3 cm, HER2+, ER-/PR-, 7+ nodes). Treated with mastectomy (with immediate DIEP flap reconstruction), AC + T/Herceptin (off label). Cancer advanced to lung in Jan. 2007 (1 cm nodule). Started Herceptin every 3 weeks. Lung wedge resection April 2007. Cancer recurred in lung April 2008. RFA of lung in August 2008. 2nd annual brain MRI in Oct. 2008 discovered 2.6 cm cystic tumor in left frontal lobe. Craniotomy Oct. 2008 (ER-/PR-/HER2-) followed by targeted radiation (IMRT). Coughing up blood Feb. 2009. Thoractomy July 2009 to cut out fungal ball of common soil fungus (aspergillus) that grew in the RFA cavity (most likely inhaled while gardening). No cancer, only fungus. Removal of tiny melanoma from upper left arm, plus sentinel lymph node biopsy in Feb. 2016. Guardant Health liquid biopsy in Feb. 2016 showed mutations in 4 subtypes of TP53. Repeat of Guardant Health biopsy in Jana. 2021 showed 3 TP53 mutations, BRCA1 mutation and CHEK2 mutation. Invitae genetic testing showed negative for all of these. Living with MBC since 2007. Stopped Herceptin Hylecta (injection) treatment in March 2020. Recent 2021 annual CT of chest, abdomen and pelvis and annual brain MRI showed NED. Praying for NED forever!!
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04-30-2008, 06:19 PM
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#18
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Senior Member
Join Date: Oct 2005
Location: New Jersey
Posts: 3,154
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Karen,
All good wishes along with prayers ae being send your way.
Hugs,
jean
__________________
Stage 1, Grade 1, 3/30/05
Lumpectomy 4/15/05 - 6MM IDC
Node Neg. (Sentinel node)
ER+ 90% / PR-, Her2+++ by FISH
Ki-67 40%
Arimidex 5/05
Radiation 32 trt, 5/30/05
Oncotype DX test 4/17/06, 31% high risk
TOPO 11 neg. 4/06
Stopped Arimidex 5/06
TCH 5/06, 6 treatments
Herceptin 5/06 - for 1 yr.
9/06 Completed chemo
Started Femara Sept. 2006
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04-30-2008, 08:21 PM
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#19
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Senior Member
Join Date: Jan 2007
Location: Thornhill, Ontario
Canada
Posts: 2,320
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Karen,I pray that this is the magic cocktail for you. Good wishes are being sent to you from Canada.all the bestcaya
__________________
ER90%+/PR 50%+/HER 2+
1.7 cm and 1.0 cm.
Stage 1, grade 2, Node Negative (16 nodes tested)
MRM Dec.18/06
3 x FEC, 3 x Taxotere
Herceptin - every 3 weeks for a year, finished May 8/08
Tamoxifen - 2 1/2 years
Femara - Jan. 1, 2010 - July 18, 2012
BRCA1/BRCA2 Negative
Dignosed 10/16/06, age 48 , premenopausal
Mild lymphedema diagnosed June 2009 - breast surgeon and lymph. therapist think it's completely reversible - hope so.
Reclast infusion January 2012
Oopherectomy October 2013
15 Years NED!!
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04-30-2008, 08:52 PM
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#20
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Senior Member
Join Date: Sep 2006
Location: Houston, Texas
Posts: 624
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Here is hoping that your new tx plan works for all three of you. I will be thinking of you and praying for you.
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