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Old 03-27-2008, 07:58 AM   #1
LOPSIDED
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Ixempra Countdown

April 1st Will Be My 6th Ixempra Treatment. I Have Been Tired, Getting Over A Cold. This Chemo Has Been Very Tolerable. I Think Back To A/C----Slept My Life Away, Taxotere----Tearing Eyes, Tired, Herceptin---No Real Problems But What A Let Down To Have Reoccurence 9 Months Into Herceptin. I Felt Like Herceptin Was Going To Be My Lifeline Back To A Normal Life. I Truly Feel That Ixempra Has Worked For Me. I Believe My Ct Will Come Out Well, Not Feeling That Sense Of Dread. I Think Once I Kick This Cold, I Will Bounce Right Back. Tykerb Will Be The Next Chapter.

Ixempra Showed A 50% Reduction In My Enlarged Lymph Nodes In My Pelvis & Abdomen After Just 3 Treatments And Next Week Will Hopefully Be My Final Treatment And I Do Feel This Chemo Has Worked, I Hope Those Of You Starting Ixempra Or May Have It In Your Future Feel Encouraged, I Know Some Chemo's Side Effects Are Pretty Tough, I Just Hope Others Find Ixempra As Tolerable As I Have.
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SHEILA (45)
09/2005--BREAST CANCER/8 POS NODES --A/C, MASTECTOMY,TAXOTERE, RADS, TAMOXIFEN,HERCEPTIN
02/2007--B/C METS TO OVARIES--HYSTERECTOMY, FASLODEX
12/2007--ENLARGING LYMPH NODES IN ABDOMEN--IXEMPRA, THEN TYKERB
08/2008--COLON TUMOR--A/C AGAIN,
12/2008--ABDOMEN TUMOR--AVASTIN/NAVELBINE FEMARA
05/2009--MET TO SPINE (L2) RADS
CURRENT TREATMENT
07/2009- START ZOMETA MONTHLY, XELODA & ABRAXANE......SURVIVING THE BEST I CAN
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Old 03-27-2008, 03:56 PM   #2
Joanne S
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Smile

That's Good News Lopsided-Sheila! I've heard positive things about Ixempra. I'm happy it hasn't been too tough on you and that it's working.



My wishes and prayers for your continued improvement and wellness!
Jo
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Old 03-27-2008, 06:27 PM   #3
tousled1
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Sheila,

That's great news the Ixempra is working for you. It is especially encouraging for me since I just had my first infusion of Ixempra today. I'm getting it every three weeks and I'm also on Tykerb/Xeloda. I hope I have as good of results as you. Congratulations to you.
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Stage IIIC Diagnosed Oct 25, 2005 (age 58)
ER/PR-, HER2+++, grade 3, Ploidy/DNA index: Aneuploid/1.61, S-phase: 24.2%
Neoadjunct chemo: 4 A/C; 4 Taxatore
Bilateral mastectomy June 8, 2006
14 of 26 nodes positive
Herceptin June 22, 2006 - April 20, 2007
Radiation (X35) July 24-September 11, 2006
BRCA1/BRCA2 negative
Stage IV lung mets July 13, 2007 - TCH
Single brain met - August 6, 2007 -CyberKnife
Oct 2007 - clear brain MRI and lung mets shrinking.
March 2008 lung met progression, brain still clear - begin Tykerb/Xeloda/Ixempra
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Old 03-27-2008, 07:09 PM   #4
Lolly
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Sheila, that is so encouraging to know you're feeling positive as you head down the home stretch. How long after the last treatment before scans, or do you know yet?

<3 Lolly
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Sept.'99 - Dx.Stage IIIB, IDC ER/PR-, HER2+++ by IHC, confirmed '04 by FISH. Left MRM, AC x's 4, Taxol x's 4, 33 Rads, finishing Tx May 2000. Jan.'01 - local/regional recurrence, Stage IV. Herceptin/Navelbine weekly till NED August 2001, then maintenance Herceptin. Right Mast. April 2002. Local/Regional recurrence April '04, Herceptin plus/minus chemo until May '07. Gemzar added from Feb.'07-April '07; Tykerb/Abraxane until August '07, back on Herceptin plus Taxotere and Xeloda Sept. '07. Stopped T/X Nov. '07, stopped Herceptin Dec. '07, started Avastin/Taxol/Carboplatin Dec. '07. Progression in chest skin, stopped TAC March '03, started radiation.

Herceptin has served as the "Backbone" of my treatment strategy for over 6 years, giving me great quality of life. In 2005, I was privileged to participate in the University of Washington/Seattle HER2 Vaccine Trial.
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Old 03-27-2008, 07:26 PM   #5
Bill
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Great news, Sheila! It's so encouraging that the Ixempra has done so well for you and the side effects tolerable. You stay strong and drink alot of water and get some rest and get rid of that cold, too. Thoughts and prayers, sweetie, Bill
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Old 03-27-2008, 07:40 PM   #6
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Sheila,
Wonderful news--praying that all keeps going well.
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Rhonda (Sassy)
dx age 45
DX 2/15/05 Stage IIb (at surgery)restaged IIIa
Left mast .9cm tumor 5 of 14 nodes
Triple Positive
4 DD A/C
12 Taxol/Herceptin
33Rads
Strange infect mast site one year aft surg, hosp 1 wk
Herceptin for total of 18 months
Lupron Monthly 4 yrs
Neurontin for aches, pains and hot flashes(It works!)
Ovaries removed 11/09 stop Lupron and Neurontin
Arimidex 6 yrs (tried Femara, no SE improvement)
Tried Exemestane-hips got so bad could hardly walk
Back to Arimidex for year seven
Zometa 2X Annual for 7years, Lasix
Stop Arimidex 5/13
Stop Zometa 7/13-Bi-lateral Stress Fractures in Femurs from Zometa
5/14 Start Tamoxifen
3/15 Stem cell transplant to stimulate femur bone growth/healing
5/15 Complete fracture of right femur/Titanium rods both femurs
9/16 Start Evista stopTamoxifen
3/17 Stop Evista--unwelcome side effects!
NED and no meds.......
14YEARS NED!
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Old 04-01-2008, 05:39 PM   #7
Faith in Him
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Shelia,

Just thinking about you. I hope your last treatment went well and keep us posted on your scan results.

Tonya
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DX 02/01/07
2.5 cm, Er/Pr-, Her2+++
18/20 Nodes
03/07 CT & Bone scan - Clear
AC x 4, Taxol x 4, Added Herceptin
Radiation until 09/07
Herceptin every 3 weeks until 06/08
01/10/08 local recurrence -IBC
01/28/08 CT & Brain MRI - clear
02/08 - Navelbine & Herceptin
05/08 -MRM
05/08 - Gemzar & Herceptin - didn't work
09/08 - Hyperthermia rads
03/09 - Tykerb/Xeloda
05/10 - Tram flap to fix wound
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Old 04-01-2008, 05:51 PM   #8
Patty F
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Congratulation Sheila today was your last treatment. I hope you are feeling well.
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10/15/07: Diagnosed at age 46 lymph node removal (2)
ER/PR - Her2 +++
11/07: Port Installed
11/07 - 1/08: AC
1/30/08: Right Mast Stage lllC
2/28/08: Start Taxol and Herceptin weekly.
5/15/08: Finished Taxol
8/12/08: Finished 33 Rads
1/29/09: Finished Herceptin
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Old 04-01-2008, 07:45 PM   #9
LOPSIDED
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Today Was Ixempra Number 6, I Am Feeling Fine---Finally Got Over That Cold. Next Week On Tuesday I Will Go For Ct Scans & A Pet Scan. I Have Never Had A Pet Scan. Then On That Friday I Will Meet With My Oncologists. The Next Two Days I Will Be Getting My Shots---Neulasta & Neupigon---I Plan To Camp Out On The Couch A Few Days.

I Will Post When I Find Out Something. I Really Want A Break From I.V. Chemo.
__________________
SHEILA (45)
09/2005--BREAST CANCER/8 POS NODES --A/C, MASTECTOMY,TAXOTERE, RADS, TAMOXIFEN,HERCEPTIN
02/2007--B/C METS TO OVARIES--HYSTERECTOMY, FASLODEX
12/2007--ENLARGING LYMPH NODES IN ABDOMEN--IXEMPRA, THEN TYKERB
08/2008--COLON TUMOR--A/C AGAIN,
12/2008--ABDOMEN TUMOR--AVASTIN/NAVELBINE FEMARA
05/2009--MET TO SPINE (L2) RADS
CURRENT TREATMENT
07/2009- START ZOMETA MONTHLY, XELODA & ABRAXANE......SURVIVING THE BEST I CAN
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Old 04-01-2008, 08:46 PM   #10
Karen W
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I am praying that the scans show results from the treatment.

Karen
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Old 04-02-2008, 06:24 PM   #11
juanita
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My prayers are with you that all goes well.
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dxd 9-04, lumpectomy,
st 1, gr 3, er,pr-, her2 +,
2 tac,33 rads,6 cmf
1 yr herceptin,
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Old 04-03-2008, 06:18 AM   #12
Mary Anne in TX
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You're incredible, Sheila! It's so good to know that you are feeling better and ready for those 3 days of couch time! Please let us know when the results are given and you're rejoicing. Much love,
ma
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MA in TX.
Grateful for each and every day....

Diag. 12/05 at age 60
Stage II, Grade 3, 4.5 cm primary tumor
ER/PR- Her2 +3 strongly positive
Her2 by FISH 7.7 amplified
vascular invasion
Ki67 20% borderline
Jan - March '06 Taxotere/Adriamycin X 3 to try to shrink tumor - it grew
April '06 Rt Modified Radical Mas, 7 of 9 nodes positive
April - Aug. '06 Herceptin/Taxol/Carboplatin X 8 (dose dense)
Sept - Dec. '06 Navelbine/Herceptin x 8 (dose dense)
Radiation & Herceptin Jan. 22 - March 1, 2007
Finished Herceptin Dec. 10 '08! One extra year.
Port removed August, 2012.
8 1/2 years since diagnosis! 5 1/2 Years NED!
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Old 04-03-2008, 08:59 AM   #13
caya
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Good luck Sheila - you deserve a break.

all the best
caya
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ER90%+/PR 50%+/HER 2+
1.7 cm and 1.0 cm.
Stage 1, grade 2, Node Negative (16 nodes tested)
MRM Dec.18/06
3 x FEC, 3 x Taxotere
Herceptin - every 3 weeks for a year, finished May 8/08

Tamoxifen - 2 1/2 years
Femara - Jan. 1, 2010 - July 18, 2012
BRCA1/BRCA2 Negative
Dignosed 10/16/06, age 48 , premenopausal
Mild lymphedema diagnosed June 2009 - breast surgeon and lymph. therapist think it's completely reversible - hope so.
Reclast infusion January 2012
Oopherectomy October 2013
15 Years NED!!
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Old 04-03-2008, 09:51 AM   #14
Ruth
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Sheila ~ I hope all goes well for you.

Hugs ~ Ruth
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[/SIGPIC]~~~~~~~~~~~~~~~~~~~~~~~~~~~

Diagnosed 6/03 nursing daughter
Dose dense A/C 4x
Modified rad mast 8/03
IDC; 3 cm; 10+/16 nodes; ER/PR-; Her2+++
Weekly taxol w/Herceptin (off label) 12x's
40 weeks Herceptin
Radiation 33x
Reconstruction w/ implants 05 & 07
NED
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