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Old 04-25-2007, 12:04 PM   #1
Cheryl44
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A/C Dense Dose (4th. and final done) start taxol/herceptin next Friday

I looked around everywhere to see if this had been talked about before because I am sure that it has, so I'm sorry if this has already been discussed many times before.

Okay, here is my question. I just completed my 4th DDose A/C treatment last Friday, but to be honest I was feeling nauseated the day I received it. In other words I never got a break from the nausea. (Yes, my doctor has tried every drug there is to help me) Soooo, does anyone have any idea when they think this nausea will end? I have been told that the Taxol/Herceptin does not cause nausea, I pray that this is true.

Let me know what you think, I am so tired of being sick to my stomach!

Thanks,
Cheryl Hamilton
LB Mastectomy
Stage IIIA
4 out of 29 lymph nodes positive
Her 2+
70% growth rate
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Old 04-25-2007, 12:33 PM   #2
Margerie
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Hi Cheryl,

My condolences, as nausea sucks! I was lucky that Emend was my ticket to a nausea-free A/C.

I experienced no nausea (needed no drugs to help me) on taxol/herceptin. Instead of being fatigued for a week, it lasted only a day or two. What was a problem was extreme dehydration. I would actually panic if I forgot to bring a water bottle. I had to use saline nasal sprays, stool softeners and vaseline the inside of my nose before I went to bed.

I didn't wan't to count on taxol being easier and then be let down if it wasn't either. But thankfully it wasn't so bad. I do know of several women that had trouble with neuropathy (I think the chance is lessened with a weekly dose) and you might want to look into supplements that may help (vit b?) I didn't have any luckily.

Good luck! I know 12 treatments may seem like a lot, but it goes by faster than you would think!
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Dx 10/05 IDC, multi-focal, triple +, 5 nodes+
MRM, 4 DD A/C, 12 weekly taxol + herceptin
rads concurrent with taxol/herceptin
finished herceptin 01/08
ooph, Arimidex, bilateral DIEP reconstruction
NED
Univ. of WA, Seattle vaccine trial '07
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Old 04-25-2007, 12:44 PM   #3
Becky
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Dear Cheryl


I was like you with the dd AC but Taxol did not make me sick. I did get numbness in my legs and fingers but it was not horrific. No nausea though!!!

Feel well. I can relate.
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Becky

Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia

NED 18 years!

Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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Old 04-25-2007, 01:50 PM   #4
MJo
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Taxol was much easier for me than A/C. I hope it's the same for you. Let us know.
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IDC, Stage I, Grade 2
Oncotype DX Score 32
Her2++ E+P+, Node Neg.
Lumpectomy 11/04/05 Clear Margins
3 Dose dense AC (Couldn't tolerate 4)
4 Dose dense Taxol & Herc. (Tolerated well)
36 weeks Herceptin (Could not complete one year due to decrease in MUGA score)
2 years of Arimidex, then three years of Femara
Finished Femara May 2011
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Old 04-25-2007, 02:04 PM   #5
LisaElder1972
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Cheryl,
I had such bad nausea with the AC that I lost 25 lbs.I had Taxotere and I only vomited twice.My problem was severe neuropathy in my legs and severe fatigue.No chemo is easier than the other for everybody because we all respond different.I have friends that sailed through Taxol like it was nothing.I hope you respond that way,you deserve a break.Good luck and let us know how it goes.Oh yeah,the Taxol is cumalitive so each treatment seems worse.But since you are on weekly it probably won't be until the last couple of weeks.

Lisa
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Old 04-25-2007, 03:48 PM   #6
Mary Jo
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Other than aches from the taxol I felt great. I never felt nauseated with taxol.

Hope the same for you.

Mary Jo
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Dx. 6/24/05 age 45 Right Breast IDC
ER/PR. Neg., - Her2+++
RB Mast. - 7/28/05 - 4 cm. tumor
Margins clear - 1 microscopic cell 1 sent. node
No Vasucular Invasion
4 DD A/C - 4 DD Taxol & Herceptin
1 full year of Herceptin received every 3 weeks
28 rads
prophylactic Mast. 3/2/06

17 Years NED

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Old 04-25-2007, 04:45 PM   #7
Susan McQ
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I was so sick on AC even taking the Emend pills, I was still sick. My onc assured me that I would not be sick on my weekly taxol/herceptin. I was not sick. I had some numbness in my toes. My problem was with the decadron given to me as a premed. It would give me a red flush on my face, neck, and chest. I also got a rash after my first infusion but it went away.

Good Luck

Susan
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dx IDC @ age 39 Feb '06
stage 2 er/pr-, her2+
neoadjuvant chemo 4 A/C completed April '06, 12 weekly taxol/herceptin completed 8/06, lumpectomy 8/15/06 NED!
33 rads completed 10/06
weekly herceptin thru May 2007 --Stopped herceptin 4/07 due to drop in LVEF. Started Herceptin again 5/07
Final Herceptin 6/12/07
Port Removed -8/13/07
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Old 04-26-2007, 08:29 AM   #8
LAURIE
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No nausea with Taxol, I felt great until half way thorugh and then the cramping got bad. The last month was not great, (face broke out and leg cramps) but I enjoyed food more than ever. No nausea at all. Skin cleared up as soon as Taxol was done (probably the steroid) and cramps are gone too. I do still have neuopathy in my fingers. Hope it goes away soon.
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Laurie
Diagonsed 8/10/06 (found own lump)at 35
Her 2 +++, er-/pr-
4 A/C 8-29-06 to 11-06
Lumpectomy, node dissection- 11/30/06
Pathology report stage IIIC
1 tumor 3 cm
10 of 15 nodes +
12 Taxol 12/18/06-03/06/07
Herceptin 12/18/06- 12/11/2007 done!!! yeah!!!
33 rads started 3/22/07, done!! yeah!! 5/07/07
Lymphedema diagonsed 2/1/07
BRCA1/BRCA2 negative
port out 1/10/08
pregnant after 6 yeas of trying- due mid feb.
Ryder David Kessel Hunter born feb.6th 2009

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