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Although it is not typical, was the patient tested for Her1 and is it positive?
Tykerb blocks Her2 and Her1. It works better if the patient is at least Her2+ as testing showed that the drug does not work well if you are only Her1 positive. If the patient is also Her1 negative, the drug would not work as it is directed at Her 2 positive patients primarily.
For the pathology you described, Avastin is commonly used. This drug prevents tumors from growing more blood vessels and actually helps the vessels they have grow to look and act more normal so that chemotherapy can be better directed to the tumor.
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Kind regards
Becky
Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia
NED 18 years!
Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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