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Diet and Nutrition By popular demand our nutritional message board. This board will be monitored by a Registered RD who is certified in oncology by the American Dietetic Association

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Old 10-08-2019, 03:11 PM   #1
R.B.
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Join Date: Mar 2006
Posts: 1,843
Re: Iodine deficiency ! - falling intakes - goitregens - competition bromine and fluo

As usual more research required!


https://journals.lww.com/oncology-ti...Cancer.13.aspx

"How Molecular Iodine Attacks Breast Cancer"
Oncology Times: December 25, 2016 - Volume 38 - Issue 24 - p 34
doi: 10.1097/01.COT.0000511599.52147.f1

Abstract

"Researchers have elucidated the mechanism of action for molecular iodine to determine how it helps protect women from fibrocystic breast condition (FBC) and confirm how it attacks breast cancer.

"Numerous studies have previously suggested iodine supplementation can promote breast health, but none had determined precisely how it worked with FBC cells. Investigators sought to identify the specific MOA that made molecular iodine effective."

"The breast cancer study focused on two common breast cancer subtypes using well-established breast cancer cell lines, MCF7 (a luminal A subtype) and MDA-MB231 (a triple-negative subtype). Cells were treated with molecular iodine at various concentrations to measure proliferation and cell death. This was subsequently followed by gene expression analysis of key important molecular markers, which are primarily responsible for cell growth and apoptosis. Primary human mammary epithelial cells derived from a healthy female donor were used as an internal control."

"Data from these studies indicated that molecular iodine has potent inhibitory effects on cell growth in both breast cancer and FBC (fibrocystic breast condition) The data also showed a dramatic increase in cell death in breast cancer cell lines used in the study and in cells derived from fibrocystic breast tissue."

"“Although several studies have, through the years, shown that molecular iodine can promote breast health and protect women from fibrocystic breast condition and potentially cancer, no one has ever identified molecular iodine's mechanism of action in fibrocystic breast condition,” said Usha Nagavarapu, PhD, study director and principal investigator of the project. “The pre-clinical investigations confirm the MOA and give the medical community reason to revisit the earlier research for clues on how best to use molecular iodine to treat and protect women.”"
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