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Tykerb Side Effects
Hi All,
I started Tykerb last Tuesday and I started experiencing pretty severe diarrhea the next day. With Imodium D, it abated for a few days and then hit me like a ton of bricks on Sunday morning (2:30 am) until 10:00 am. The Imodium took that long to work. Today I'm much better.
Has anyone else had a similar experience? I'm not taking Xeloda with the Tykerb. In fact, my last chemo (taxotere) was almost 4 weeks ago and the only other drug I take is Zometa (also 4 weeks ago.) However, I did start a course of prednisone last Tuesday also to address a chronic cough that I've had since my pleuradesis last January. The prednisone is working like a charm - thankfully. But I don't think it causes diarrhea.
I'm so happy to finally be on Tykerb but I hope that the diarrhea doesn't become a chronic problem.
Oy - if its not one thing, its another, in the immortal words of Gilda!
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Debbie
8/96 - Diagnosed Stage I - 1.8 cm tumor in left breast
0+ lymph nodes, ER+/PR-
Lumpectomy, radiation, CMF x 9, Tamoxifen
6/99 - Stage IV - 1.2 cm tumor in left lung, HER2 NEU +
VATS thoracotomy, Herceptin and Arimidex
2000 - Bone mets to left scapula and right ribs
Herceptin; Taxol x 9, Zometa
2/2001- Rt. lung - 6 mm tumor
Mini-thoracotomy
2/2001 - 12/2006
Xeloda-10 months, Navelbine-10 months,
Gemzar, Abraxane, Taxol/Carboplatin x 10, Aromasin, Faslodex,
Zoladex, Tamoxifen
2001 - Radiation to left scapula for pain managenent
9/2004 CyberKnife to right rib
7/2006 - Pleural effusion - thoracentesis performed twice
1/2007 - Pleuradesis and Taxotere x 5
4/2007 - Stopped Herceptin after 8 years (weekly).
Started Tykerb with Taxotere but stopped after 10 days
5/2007 - Stopped Taxotere, restarted Tykerb and Herceptin
Currently on Tykerb, Herceptin, Zometa
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