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Old 03-31-2005, 02:10 PM   #1
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Has anyone who has had Her2 also have Psoriasis. My concern is that even they are not related, they both are caused by the multiplying of cells.

Just wondered if anyone has had this happen to them. I have. I was Her2 Pos IIB in May of 2001. I had the chemo, radiation, including Herceptin for one year, once a week, and then once every 3 weeks for 8 months after that.

I am NED, but have Psoriasis. When I was taking Herceptin, the Psoriasis was gone but returned when I ended Herceptin.

Thank you for any info you all might have and God Bless.
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Old 04-02-2005, 08:18 PM   #2
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I have friends who have psoriasis but do not have cancer. They are the only people I know with this disorder, and it is difficult to control.

None of my cancer survivor friends (any kind of cancer) has psoriasis that I have heard about. Cannot think of a link between the two. We get all kinds of disorders that are caused by cells multiplying and not Her2 related.

Hope you are able to get that itchy rash under control again. Maybe it is nerves?
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Old 04-03-2005, 03:17 PM   #3
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I have two quarter size spots on my scalp. I have not been bothered by them, since I began taking Herceptin 8 months ago. I did not realize this, until you asked the question. Curious, indeed. I will ask my oncologist about it.

I am in stage IV, HER2 3+ @ greater than 90% and I will be taking Herceptin for some time to come.
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Old 04-08-2005, 03:38 PM   #4
*_Linda in Chicago_*
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Very interesting that you should ask that. My twin sister passed away from breast cancer and never had it. I got it 30 years ago when I was 18 and it has been with me on and off. No one else in my family has had it. It stopped when I was pregnant 15 years ago and then comes back, usually on the elbow but was horrible when I first got it and I tried everything.

It was all over my body face and scalp. Finally it was calmed down with steroid creams and saran wrap. Now I have Skin Cap which my dermatoligist stocks and of course insurance doesn't cover.

Was wondering about anyone having it and cancer.

Linda in Chicago
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Old 03-17-2015, 06:37 PM   #5
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Re: Her2 and Psoriasis


I was researching rapid cell growth and overexpression and found the above link. Quite interesting. (The HER2 link also popped up, so I thought I'd post here).

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Old 03-28-2015, 08:26 AM   #6
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Re: Her2 and Psoriasis

I used to get fairly frequent outbreaks of eczema on the palms of my hands. Since I began being treated for HER-2+ breast cancer I've had fewer outbreaks and they are much milder. In fact, it's practically cured. I mentioned this to my oncologist. She thought it was interesting.

Given a choice, I'd keep the eczema and ditch the breast cancer, but of course I don't have that choice.
4/19/11 Diagnosed invasive ductal carcinoma in left breast; 2.3 cm tumor, 1 axillary lymph node, weakly ER+, HER2+++
4/29/11 CT scan shows suspicious lesions on liver and lungs
5/17/11 liver biopsy
5/24/11 liver met confirmed--Stage IV at diagnosis
5/27/11 Begin weekly Taxol & Herceptin for 3 months (standard of care at the time of my DX)
7/18/11 Switch to weekly Abraxane & Herceptin due to Taxol allergy
8/29/11 CT scan shows no new lesions & old lesions shrinking
9/27/11 Finish Abraxane. Start Herceptin every 3 weeks. Begin taking Arimidex
10/17/11--Brain MRI--No Brain mets
12/5/11 PET scan--Almost NED
5/15/12 PET scan shows progression-breast/chest/spine (one vertebra)
5/22/12 Stop taking Arimidex; stay on Herceptin
6/11/12 Started Tykerb and Herceptin on clinical trial (w/no chemo)
9/24/12 CT scan--No new mets. Everything stable.
3/11/13 CT Scan--two small new possible mets and odd looking area in left lung getting larger.
4/2/13--Biopsy of suspicious area in lower left lung. Mets to lung confirmed.
4/30/13 Begin Kadcyla/TDM-1
8/16/13 PET scan "mixed," with some areas of increased uptake, but also some definite improvement, so I'll stay on TDM-1/Kadcyla.
11/11/13 Finally get hormone receptor results from lung biopsy of 4/2/13. My cancer is no longer ER positive.
11/13/13 PET scan mixed results again. We're calling it "stable." Problems breathing on exertion.
2/18/14 PET scan shows a new lesion and newly active lymph node in chest, other progression. Bye bye TDM-1.
2/28/14 Begin Herceptin/Perjeta every 3 weeks.
6/8/14 PET "mixed," with no new lesions, and everything but lower lungs improving. My breathing is better.
8/18/14 PET "mixed" again. Upper lungs & one spine met stable, lower lungs less FDG avid, original tumor more avid, one lymph node in mediastinum more avid.
9/1/14 Begin taking Xeloda one week on, one week off. Will also stay on Herceptin and Perjeta every three weeks.
12/11/14 PET Scan--no new lesions, and everything looks better than it did.
3/20/15 PET Scan--no new lesions, but lower lung lesions larger and a bit more avid.
4/13/15 Increasing Xeloda dose to 10 days on, one week off.
7/1/15 Scan "mixed" again, but suggests continuing progression. Stop Xeloda. Substitute Abraxane every 3 weeks starting 7/13.
10/28/15 PET scan shows dramatic improvement everywhere. All lesions except lower lungs have resolved; lower lungs noticeably improved.
12/18/15 Last Abraxane. Continue on Herceptin and Perjeta alone beginning 1/8/16.
1/27/16 PET scan shows cancer is stable.
5/11/16 PET scan shows uptake in some areas that were resolved on the last two scans.
6/3/16 Begin Kadcyla and Tykerb combination
6/5 - 6/23 Horrible diarrhea from K&T together. Got pneumonia.
7/15/16 Begin Kadcyla only every 3 weeks.
9/6/16 Begin radiation therapy on right lung lesion that caused the pneumonia.
10/3/16 Last of 12 radiation treatments to right lung.
11/4/16 Huffing and puffing, low O2, high heart rate, on tiniest bit of exertion. Diagnosed as radiation pneumonitis. Treated with Prednisone.
11/11/16 PET scan shows significant improvement to radiated part of right lung BUT a bunch of new lung lesions, and the bone met is getting worse.
11/22/16 Begin Eribulin and Herceptin. H every 3 weeks. E two weeks on, one week off.
3/6/17 Scan shows progression in lungs. Bone met a little better.
3/23/17 Lung biopsy. Tumor sampled is ER-, PR+ (5%), HER2+++. Getting Herceptin and Perjeta as a maintenance treatment.
5/31/17 Port placement
6/1/17 Start Navelbine & Tykerb
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