Abraxane VS Taxotere ?
Hi Ladies,
I'm scheduled to start Taxotere this coming Weds. along with my Herceptin. It seems that the Herceptin alone, is not going to be enough to bring my Tumor Markers back down. I've been back on Herceptin since August 6th, and my Her2 Serum and CA 15-3 went down slightly initially, but both have started to climb back up.
My doctor and I discussed possible options, and decided to give Taxotere a try again, since it worked so well for me back in 2001/2002.
Naturally I've been reading alot the last few days, and am now second guessing the whole Taxotere regime. I've read that Abraxane has better response rates with fewer side effects, so am naturally curious as to why my doctor didn't mention it.
Any input or personal experience would be appreciated, so I can arm myself when I talk to him about it this week.
Thanks!
Kim
PS: I didn't even ask him about Tykerb or Pertuzamab because I'm thinking that saving those for later might be in my best interest. I really don't have a clue what the right or best thing is, just wanting to nip this thing in the bud!
__________________
Diag. Feb 1997 4.5cm IDC <10%ER+, PR-. 5 out of 36 nodes +. Mastectomy followed by 3 rounds Adriamycin/Cytoxin.
5/1997 Hi Dose Chemo w/ Stem cell rescue. Spent 4 weeks in isolation ward. Then 6 weeks radiation.
9/2001 widespread mets to liver. 8 mos Taxotere/Herceptin brought me almost to NED. Stop Taxotere & add Femara .
11/2002 liver resection to remove spot that turned out to be necrosis. Officially NED!
7/2003 Tumor markers rising add Xeloda Disastrous reaction, 8 days hospital, but tumor markers came back to normal!
June -Dec 2004 UW Vaccine Trial.
7/2005 MRI single 11mm brain met
8/2005 Gamma Knife.
Brain MRI @3 months NED!
2006-2011 brain/body still NED
8/04/11 Taking Herceptin break, will monitor with tumor markers.
6/20/12 Tumor markers begin to rise. CA15-3 is 31.3 and Her2 Serum is at 17.1 Decide to repeat in one month.
7/23/12 CA15-3 now 49.3
Her2 Serum 26.8
8/6/12 Back on Herceptin
CA15-3 now 76
Her2 Serum now 49
11/7/12 Add weekly Taxotere for 4 cycles
2/2013 Stopped Taxotere added Perjeta. MRI shows approx. 50% reduction liver mets. CA15-3 still elevated @ 55. Will continue on just Herceptin & Perjeta.
November 2014 Continuing on Herceptin, Perjeta, and
Femara indefinitely. Guess I'm NED again, but watching those tumor markers carefully!
Dec. 2015 PET scan reveals mass in perirectal area of abdomen.biopsy confirms. Still Her2+, but no longer ER+. Bye bye Femara
Jan 2016 Begin Kadcyla
March 2016 PET scan shows tumor now barely visible, still NED everywhere else.
2016/2017 continue Kadcyla
November 2017 brain MRI reveals small focus of T2 hyperintensity with possible 4mm enhancing nodule. Short term follow up MRI suggested. Stay tuned...
|
Threaded Mode