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04-10-2007, 11:12 PM
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#1
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Senior Member
Join Date: Sep 2005
Location: .
Posts: 211
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recurrence
Recurrence affirmed p more chest wall nodules. i begin herceptin and taxotere on friday. Am now reaching end of chemo line.
love
linda
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04-11-2007, 02:37 AM
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#2
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Senior Member
Join Date: Sep 2005
Location: Melbourne Victoria
Australia
Posts: 330
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thinking of you
Dear Linda
Sad to hear about your recurrence. Hang in there. I am thinking of you and saying some prayers.
Jackie
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04-11-2007, 05:24 AM
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#3
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Senior Member
Join Date: Sep 2005
Posts: 589
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Linda,
I'm sorry to hear about your news but not convinced that your approaching the end of the chemo line as there are always new drugs in the pipeline and who says you can't go back onto something that worked well for you in the past (depending on the timeframe). I can imagine how anxious you must be.
Eric
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04-11-2007, 05:25 AM
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#4
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Senior Member
Join Date: Jun 2006
Location: San Antonio, TX
Posts: 2,357
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Hello Linda! So sorry to hear that you must start Taxotere and Herceptin on Friday, but am glad it is there for you until they find the thing that will keep those things from popping up on you. Don't lose faith in the system coming up with new drugs and understanding of Her2 bc. When I dispair, I try hard to remember that I'm not dependent on me for help, but on God and those he provides in my life. One day at a time. Lots of prayers will go with you on Friday as you do your part to stop this stuff in it's tracks! Lots of love, ma
__________________
MA in TX.
Grateful for each and every day....
Diag. 12/05 at age 60
Stage II, Grade 3, 4.5 cm primary tumor
ER/PR- Her2 +3 strongly positive
Her2 by FISH 7.7 amplified
vascular invasion
Ki67 20% borderline
Jan - March '06 Taxotere/Adriamycin X 3 to try to shrink tumor - it grew
April '06 Rt Modified Radical Mas, 7 of 9 nodes positive
April - Aug. '06 Herceptin/Taxol/Carboplatin X 8 (dose dense)
Sept - Dec. '06 Navelbine/Herceptin x 8 (dose dense)
Radiation & Herceptin Jan. 22 - March 1, 2007
Finished Herceptin Dec. 10 '08! One extra year.
Port removed August, 2012.
8 1/2 years since diagnosis! 5 1/2 Years NED!
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04-11-2007, 08:22 AM
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#5
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Senior Member
Join Date: Sep 2005
Location: Philadelphia
Posts: 301
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Linda-
I have nodes in the chest wall area too - what has worked for you and what hasn't, as I am about to change treatments as well? Am thinking of you...
Regards,
__________________
Shell
init diag 3/17/03-stage IIIC
ER-/PR-/HER2+++
CET x4 neo-adjuvant
lump & SNB 8/03
CET x2
radiation and herceptin/navelbine 11-03-1/04
1st reoccur to lymph nodes 8/04
complete axillary dissection 12/04
herceptin/taxotere til progression (lungs) 3/05
xeloda w/out lapatinib trial 6/05
lapatinib/tykerb added 4/06
ended trial 8/06 due to progression
doxil / avastin 11/06-12/06 - wasn't working
navelbine/herceptin/avastin 12/06/3/07 - progression
gemzar/carboplatin/tykerb 4/07
mri shows extensive mets to bone in pelvic area 6/07
switched to abraxane (3 on/1 off) + tykerb 6/07
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04-11-2007, 12:50 PM
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#6
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Senior Member
Join Date: Sep 2006
Location: Houston, Texas
Posts: 624
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Best wishes to you. I am sorry that you have to start chemo again.
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04-11-2007, 07:53 PM
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#7
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Senior Member
Join Date: Dec 2006
Posts: 136
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Linda -
There certainly isn't much to say to boost your spirits right now. Just know we are thinking about you. There has to be something else out there for you to keep those nodules under control. I see so many posts where treatment options were back to square one and keeping things at bay.
Hugs to you as you endure yet another battle.
__________________
Debra
Diag. 11/05 at age 40 triple positive
3.8 cm tumor and 9 mm tumor
Stage IIb/SN positive(no other nodes)Grade 3
Bilat. mastect. 12/05 (Rt.prophylactic) followed with AC/taxol/Herceptin/tamoxifen then switched to arimidex after hysterectomy in 12/06. August 07 switched to Aromasin due to severe jt. pain from Arimidex. Nov. 2011 No more meds and NED!
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04-11-2007, 08:15 PM
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#8
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Senior Member
Join Date: Aug 2001
Location: Oregon
Posts: 1,756
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Linda, I am so sorry to hear this, but I know you are not at the end of your options! Here's a link to the Articles page, with another link to a site listing all the drug options for bc...hope this helps. And as Eric points out, buying time until the next drug that's in the pipeline is available is what it's all about. I know right now you feel hopeless and tired, and no wonder. We have been through the mill and sometimes it just gets too much, but hang in there my friend. We're here for you. <3 Lolly
Common Breast Cancer Drugs:
http://www.thebreastcaresite.com/een...256CCA00623800
__________________
Sept.'99 - Dx.Stage IIIB, IDC ER/PR-, HER2+++ by IHC, confirmed '04 by FISH. Left MRM, AC x's 4, Taxol x's 4, 33 Rads, finishing Tx May 2000. Jan.'01 - local/regional recurrence, Stage IV. Herceptin/Navelbine weekly till NED August 2001, then maintenance Herceptin. Right Mast. April 2002. Local/Regional recurrence April '04, Herceptin plus/minus chemo until May '07. Gemzar added from Feb.'07-April '07; Tykerb/Abraxane until August '07, back on Herceptin plus Taxotere and Xeloda Sept. '07. Stopped T/X Nov. '07, stopped Herceptin Dec. '07, started Avastin/Taxol/Carboplatin Dec. '07. Progression in chest skin, stopped TAC March '03, started radiation.
Herceptin has served as the "Backbone" of my treatment strategy for over 6 years, giving me great quality of life. In 2005, I was privileged to participate in the University of Washington/Seattle HER2 Vaccine Trial.
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04-11-2007, 08:43 PM
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#9
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Senior Member
Join Date: Sep 2005
Location: Central Coast, CA
Posts: 3,207
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Well, poo! Back in the saddle again. I agree, there may still be many options - going back to ones that worked for you in the past can sometimes be effective again, and there are so many new treatments available. Do not lose heart - just another bump in the road.
Much love
Chris
__________________
Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial
5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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