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11-19-2007, 12:29 PM
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#1
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Senior Member
Join Date: Nov 2005
Location: Northern Calif.
Posts: 981
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Barbara,
Such good news! I am happy that you are feeling well enough to teach. I wish you continued success.
Hugs,
Lexi
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11-19-2007, 03:08 PM
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#2
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Senior Member
Join Date: Sep 2005
Location: Newton, MA
Posts: 951
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To Eric
Hi Eric,
I was never on Tykerb. Herceptin alone worked for me for 1 1/2 years. When I started on it I had a 3 cm brain met, skin mets, and lung, and liver mets, but no bone mets. It wiped everything out, but bone mets appeared. I then went on Navelbine, but started to progress at this time last year. I then had a biopsy, but it didn't show if my ER/PR markers had changed. I then waited for this trial and am now in it. As I stated before, it is very easy to tolerate. Herceptin has kept my other mets at bay.
Best wishes,
Barbara H.
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11-19-2007, 07:08 PM
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#3
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Senior Member
Join Date: Sep 2005
Posts: 589
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thanks Barbara
Looking forward to continued great news for and from you.
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11-20-2007, 09:39 PM
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#4
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Senior Member
Join Date: Sep 2005
Posts: 556
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Barbara,
Great news, wish you continued success on this trial.
Julie
__________________
Diagnosed in Sept 2004 while pregnant with the second child. Stage 3b, tumor 4.5cm, 4 auxillary and supraclav node positive. Her2+++ FISH 9.4 and er-,pr-.
Had dose dense neoadjuvant AC,Taxol then mastectomy,radiation+xeloda+Herceptin.
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11-21-2007, 02:57 PM
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#5
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Senior Member
Join Date: Oct 2007
Posts: 47
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Barbara,
Reading your post this evening before Thanksgiving has given me one more thing to be grateful for. I'll private email you after the holidays to see if you would like to get together! I'd love it.
Warm regards, Patrice
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11-27-2007, 09:37 AM
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#6
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Senior Member
Join Date: Nov 2007
Posts: 210
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Barb.. any updates... how many doses have u received.. what dose are u getting..
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12-20-2007, 07:04 PM
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#7
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Senior Member
Join Date: Sep 2005
Location: Newton, MA
Posts: 951
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Doing Great!!!
Hi Everyone,
I had a bone and cat scan last week and saw my oncologist today. My cat scan looks good and my bone scan indicates that the bones are healing. My tumor markers are great indicators for me and are now both normal. My CEA is now 1.7. I am hoping that it will eventually be under one. This is a great trial and I highly recommend it . It has minimal side effects, and I can live a normal life and continue working. I am on the phase 1 weekly trial.
Best wishes,
Barbara H.
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12-20-2007, 07:58 PM
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#8
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Senior Member
Join Date: Feb 2006
Location: Acworth, GA
Posts: 2,104
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Barbara,
Such great news and couldn't come at a better time of year. Congratulations. Praying for you that the trial continues to give you great results.
__________________
Kate
Stage IIIC Diagnosed Oct 25, 2005 (age 58)
ER/PR-, HER2+++, grade 3, Ploidy/DNA index: Aneuploid/1.61, S-phase: 24.2%
Neoadjunct chemo: 4 A/C; 4 Taxatore
Bilateral mastectomy June 8, 2006
14 of 26 nodes positive
Herceptin June 22, 2006 - April 20, 2007
Radiation (X35) July 24-September 11, 2006
BRCA1/BRCA2 negative
Stage IV lung mets July 13, 2007 - TCH
Single brain met - August 6, 2007 -CyberKnife
Oct 2007 - clear brain MRI and lung mets shrinking.
March 2008 lung met progression, brain still clear - begin Tykerb/Xeloda/Ixempra
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12-20-2007, 08:27 PM
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#9
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Senior Member
Join Date: Sep 2005
Posts: 589
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Barbara - FANTASTIC!!!! What great news. A CEA of 1.7 indicates that you are well within the normal range. What a great way for you to celebrate the new year. This appears to be a very exciting new drug and you and Lily are wonderful trailblazers.
Eric
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12-20-2007, 08:59 PM
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#10
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Senior Member
Join Date: Nov 2007
Posts: 210
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this is great news barb... how do they do the weekly dose.
the phase 2 trial dose is 3.6 mg/m2 .. what is the weekly dose you are on...
run to live
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12-20-2007, 10:40 PM
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#11
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Senior Member
Join Date: Mar 2007
Location: CHARLOTTE NC USA
Home town (ECUADOR) South America
Posts: 542
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Dear Barbara ...you was one of the main reason to get me on this trail ...when I ask my Doc about trials he mentioned about this and in a second I remember your post ...and get exited ...and ask for it ...after all the test I think I did a great choose because my ct scan are great , my Doc said ...and thanks to you ..I really hope so that another Lady's on this site get in to ..like us ...plus my thoughts was genentech need all her costumer back (because is for patient who herceptin fail) so that way they still doing so a great sales in the future ....congratulalion you ct scan give me more hope ...like mine also give hope for somebody else ...
__________________
Lily Diag April/06 5 months after give birth my son Max stage IV mets on liver (5 tumors) 38 year old, her2+++ and ER+PR+ from32 nodes 4 positives mastectomy right breast chemo before surgery herceptin/carboplatin/taxotere ,clear and surgery have radiation 20, `& then herceptin and tamoxifen NED until Aug/07 body only then 'n June 04-06-07 .1 lesion of 1.6 cm on cerebellum ...novalis ,open sugery 5m.m brain met again novalis, 4mm.In the liver. Waiting 2 months now 3 tumors enroll on T-MCC trial start first infusion Nov 5/07 at Dec 17 scan show one tumor despair the 2nd and 3th diminish Doc said great results until March/08 ct scan show progression 03-05-08 start tykerb & xeloda
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12-21-2007, 07:13 AM
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#12
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Senior Member
Join Date: Oct 2007
Location: Australia
Posts: 309
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Dear Barbara and Lily - so glad this trial seems to be working so well for both of you! ((Big Hugs)) Wonderful!
Blessings
Hermiracles
__________________
2003 L/DCIS –> LWE: High G./Comedo - 6 nodes clear 6 wks Rx
04/07 2 miracles born ~ very grateful
06/07 Susp areas L/b
09/07 Stage 2 bilat. mastectomy R/ b. clear extens DCIS/IDC Paget’s 8 nodes clear ER(<5%) HER2+++ CT clear
11/07 Portacath - FEC
15/11/07 Stage 4 Emerg op - hip replacemt #NOF bone mets H/Taxotere
12/07 Rx to 'spots' on spine/R/hip/femur 3wkly H
2008 H+T mets to rib/sternum? Aredia CT clear! Cont. H + Aredia 07/08 1 wk Palliative Care - mets to lungs + ?1 to brain
09/08 Stop H complete Epirubicin 1wk PC new brain mets
10/08 2wks WBR 1wk PC 22/10/08 Tykerb/Xeloda 12/08 6 CEREBRAL METS COMPLETELY GONE! Rib mets down to <1cm.
01/09 Tumour markers normal! Rx to L/arm
03/09 LUNGS CLEAR (ALL NODULES GONE!), brain clear, liver clear. Bones stable! ~ THANK YOU GOD
07/09 Repeat CT Scan ~ ALL organs clear apart from bones which remain stable. I walk in gratitude.
***************
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12-21-2007, 02:03 PM
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#13
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Senior Member
Join Date: Oct 2007
Posts: 47
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Barbara, what great news & wonderful way to start the New Year. You'll continue to be in my thoughts and prayers.
Warm regards, Patrice
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12-21-2007, 06:23 PM
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#14
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Senior Member
Join Date: Nov 2005
Location: Lincoln, Rhode Island
Posts: 371
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Dear Barbara,
What wonderful news I am so happy for you. Have a wonderful holiday. You are always in my thoughts and prayers. Please keep us posted on how you are doing.
__________________
Love and Hope
Karen
IDC
DX 1998 STAGE I ER+/ PR+
AC CHEMO TILL FEB 1999
Tamxofin till 2001
2001 exstensive liver mets and mets to lungs
Started weekly taxol
Jan 2002 found out I was strongly HER2POS+++ started herceptin continued with taxol and herceptin till June 2002 then from June 2002 till Jan 2005 just herceptin and Arimidex
2005 Navelbine herceptin had RFA Then back on taxol with herceptin
April 2006 progression again went on clinical trial with tykrerb/herceptin progressed on the started Xeloda/ herceptin
Feb 2007 started Doxil
August 2007 Taxotere,Carboplatin and Herceptin exstensive mets to liver and pancreas
October 2007 Had to stop Carboplatin due to sever allergic reaction
Jan 2008
Stopped Taxotere due to progression now on Gemzar and Herceptin
March 2008 Starting Carboplatin, Abraxane, and Herceptin.
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01-27-2008, 10:42 AM
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#15
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Senior Member
Join Date: Jun 2007
Posts: 34
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mcc- dmi trial
I am very much interested in this trial. Can anyone tell me about it? What are the requirements ? I had taken hercepton for over 2 yrs. till I had progression. Please anyone? Are these trials at certain places? Thanks linda
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01-27-2008, 12:31 PM
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#16
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Senior Member
Join Date: Sep 2005
Location: Newton, MA
Posts: 951
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Go to Lily's site. There is a post that gives information about the trial. I am on phase 1, but there are more places that are offering the phase 2 trial.
Good luck,
Barbara
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01-28-2008, 03:32 PM
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#18
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Senior Member
Join Date: Jun 2007
Posts: 34
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Thanks run to live, I appreciate the info and article and plan to talk about this with my onc. As part of the requirement it says no more than 3 different chemos. Does that mean 3 different chemo regimens ? The first regimen I had was taxotere and gemzar,and herceptin together. Does that count as 1 0r 2? thanks mykentuckyhome
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01-28-2008, 03:38 PM
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#19
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Senior Member
Join Date: Sep 2005
Location: Newton, MA
Posts: 951
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You will have to speak with your oncologist about the chemo. I am not sure.
Barbara
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01-28-2008, 03:46 PM
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#20
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Senior Member
Join Date: Nov 2007
Posts: 210
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that is one regimen.. but make the call.. dont delay.. dont give the cancer even one extra day inside your body...
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