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Old 09-26-2012, 03:22 PM   #1
ANelson
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Join Date: Aug 2012
Location: Live in Atlanta,Ga
Posts: 7
Started TDM1 clinical trial in Nashville

Hey ladies
I just began a clinical trial for TDM1 in Nashville and had my first infusion on Sept 18. It has been two days of flu like symptoms and severe migraine headaches subsiding finally on Monday September 24 with the help of 2mg of steroids, which I reduced to 1 mg yesterday and didn't rake any today. Has anyone been told to take steroids? They really do a number on me with swelling me up and i have difficulty keeping still, that is why I am so cautious in the amount I take. They have seen an increase in my liver enzymes as well based on the labs that were completed yesterday. What other experiences have you all had on TDM1? Any suggestions? I am hoping this will be the answer to my prayers. Thanks in advance for your time.

Angie
__________________
Diagnosed Stage IV Breast Cancer in August 2011 Her2+ Er-pr-
Metastic to liver
8 rounds Abraxaine (3 weeks on 1 week off) and Herceptin (once weekly)
April 2012 stopped Abraxaine, Herceptin only every three weeks. (liver and breast tumors shrank considerably but not NED)
June 2012 CT scan showed enlarged axillary lymph node not responding. Biopsy of node revealed same cancer. Surgeon recommended breast MRI. MRI revealed new area in left breast 6mm. Breast biopsy revealed same cancer. Surgeon not sure if we should do surgery.
7/29/12 CT scan to see if spreading anywhere else. Awaiting results to determine plan of care. Will meet with oncologist 8/7/12
8/7/12 no progression in liver. No evidence of disease anywhere else. Dr recommending TDM1 trial in Nashville. Waiting.
9/18/12 Began TDM1 in Nashville. Hopeful!!
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