Weekly Herceptin versus Triple dosage??

[syncmaster174v]

Is anyone able to shed some light on the following? I can't find it in the medical literature.

I am told by my oncologist that the FDA approved Herceptin given weekly - but she also admininsters it every two weeks at double the dose as well as triple the dose every three weeks.

Does anyone have any literature/research I could read about the triple dose of Herceptin administered every three weeks?
I'm concerned about it's safety as well as how effect can it be given every three weeks? - do the antibodies stay effective for that length of time?

On the positive side, I will be returning to teaching in the fall and it would be very difficult to go weekly. I am planning to try triple the dose every three weeks - but I would like to find out where it is done plus any studies on this frequency of dosage.

Thanks for whatever leads you can give.