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Old 06-11-2008, 10:46 AM   #10
R.B.
Senior Member
 
Join Date: Mar 2006
Posts: 1,843
This is about cardiac health and not BC. I post it because it is unusually unequivocal in its statements on the benefits of omega 3s.

It seems to me that anything that assists with cardiac health is good news; it would be nice if they looked to see if omega 3s helped reduce any cardiac implications of Herceptin.

http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum

Am J Clin Nutr. 2008 Jun;87(6):1991S-6S.
Fish and n-3 fatty acids for the prevention of fatal coronary heart disease and sudden cardiac death.
Mozaffarian D.

Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Department of Epidemiology and Nutrition, Harvard School of Public Health, Boston, MA, USA. dmozaffa@hsph.harvard.edu

Large observational studies, randomized clinical trials, and experimental studies have evaluated the effects of fish and n-3 fatty acid consumption on fatal coronary heart disease (CHD) and sudden cardiac death (SCD), clinically defined events that most often share the final common pathway of fatal ventricular arrhythmia. These different study designs, each having complementary strengths and limitations, provide strong concordant evidence that modest consumption of fish or fish oil (1-2 servings/wk of oily fish, or approximately 250 mg/d of EPA+DHA) substantially reduces the risk of CHD death and SCD. Pooled analysis of prospective cohort studies and randomized clinical trials demonstrates the magnitude and dose-response of this effect, with 36% lower risk of CHD death comparing 0 and 250 mg/d of EPA+DHA consumption (P < 0.001), but then little additional benefit with higher intakes. Reductions in risk are even larger in observational studies utilizing tissue biomarkers of n-3 fatty acids that more accurately measure dietary consumption. The concordance of findings from different studies also suggests that effects of fish or fish oil on CHD death and SCD do not vary depending on presence or absence of established CHD. The strength and consistency of the evidence, and the magnitude of this effect are each notable. Because more than one-half of all CHD deaths and two-thirds of SCD occur among individuals without recognized heart disease, modest consumption of fish or fish oil, together with smoking cessation and regular moderate physical activity, should be among the first-line treatments for prevention of CHD death and SCD.
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