Does chemotherapy get harder?

[cjjhero]

My sister is nearly finished with her chemotherapy. She is receiving the TCH chemo and also neulasta.

She doesn't really get many side effects from the TCH therapy. She'll get a little nauseated, tired but that's about it from the chemotherapy. The next few hours after the neulasta she is completely wiped out. She experiences loss of appetite, bone pain, serious mood swings, depression and anxiety. My sister suffers from agoraphobia and general panic disorder prior to her diagnosis. So these new anxieties send her over the edge.

Her irrationality really sets in with not wanting to even drink or eat anything. She's lost about 40 pounds in 3 months since she started chemotherapy. She starts to recover about a week after the neulasta. She will start being more rational and eating normally and her old self a week prior to chemotherapy.

Her doctor told us that she will still receive herceptin every 3 weeks for a year. She will have surgery approximately 6 weeks after the final chemo ends which is about July 2. She's nearly done. The tumor has shrunk which is why the surgery is following chemo.

Her white blood counts and completely normal. She was a very healthy person prior to her diagnosis.

She is on round 4 of chemotherapy. She will do 6 rounds total. Will it get harder or easier?
Thanks

She is stage 2b with 1 lymph node maybe affected.