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Old 07-17-2010, 08:50 AM   #1
weety
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aredia for osteopenia???

Hi all,
I am looking for info on using aredia for osteopenia. I was diagnosed at age 38 (stage 1) completed TCH and currently finishing up herceptin. Also had an ooph/hyster so am now on an AI. At first my onc had told me she could "probably" give me zometa off-label for the prevention of osteoporosis if my bone density scan came back with problems. I fit all of the osteo risks (thin, petite, white female) and I have been following the new studies about the reduction of recurrences, so I was pretty excited about being able to possibly get the zometa.

Now that I have my results back (osteopenia) she is retracting what she told me (BUMMMMMER!) and said she could instead offer me aredia. I can't find much info on aredia for osteopenia. I also am looking for info on zometa for osteopenia/osteoporosis prevention. She told me she needs some studies to back it up if I want the zometa--I'm determined to find them unless aredia is also a good bisphos to use (in terms of possible recurrence reduction rates) as well.

Please help!!! I'm having trouble finding the info I need.
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Diagnosed 7/09 with 7mm IDC ER weakly +, PR -, Her2+

TCH chemo 8/09-12/09

Ooph/hysterectomy 4/10

Started Femara 6/10

Completed year of herceptin 10/11

Zometa 1/11 (2X/yr for 2yrs)

Hopefully nothing else!!!!
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Old 07-17-2010, 04:18 PM   #2
tricia keegan
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Re: aredia for osteopenia???

I think they're both fairly similar but Aredia is older http://www.pamidronate.com/index.jsp
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Tricia
Dx July '05 IDC 1.9cm Triple positive 3/9 nodes positive
A/C X 4 ..Taxol/Herceptin x 12 wks then herceptin 1 yr
Rads x 36 ..oophorectomy August '06
Currently taking Arimidex..
June 2011 osteopenia/ zometa x1 yearly- stopped Zometa 2015 as Dexa show normal bone density.
Stopped Arimidex July 2014- Restarted Arimidex 2015 for a further two years on the advice of my Onc.
2014 Normal Dexa scan
2018 Mammo all clear, still NED!
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Old 08-09-2010, 06:11 PM   #3
Jackie07
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Re: aredia for osteopenia???

Just read this today on WebMD:

Osteoporosis is often called the "silent disease." That's because most of the time, bone loss occurs without any symptoms at all. But when osteoporosis becomes severe, it can lead to fractures and a condition called kyphosis. Kyphosis is spinal compression, sometimes described as the "dowager's hump." Both fractures and kyphosis can be very painful. This pain is usually more severe than the typical "aches and pains" many people feel as they get older.
Fractures and Compression Cause Osteoporosis Pain

The most common cause of osteoporosis pain is a spinal compression fracture. If you have been diagnosed with osteoporosis, or if you have several risk factors for osteoporosis, these symptoms may indicate a compression fracture:
  • <LI sizset="159" sizcache="9">Sudden, severe back pain that gets worse when you are standing or walking
  • Some pain relief when lying down
  • Pain and difficulty in twisting or bending
  • Loss of height
  • Curvature of the spine
Bones are fragile in osteoporosis. Fractures and osteoporosis pain can occur even from simple movements that don't seem dangerous. Examples of these movements include lifting a bag of groceries, twisting to get out of a car, or tripping slightly on a rug or step.
Fractures can take months to heal. The pain should start to go away as the healing process progresses. However, for some people osteoporosis pain can become chronic. Your doctor can recommend options for managing and reducing pain. These options include medication and other therapies.
Medication to Relieve Osteoporosis Pain

Medication is the most popular way to manage osteoporosis pain. Medications include these:
  • Over-the-counter pain medications like acetaminophen, aspirin, ibuprofen, naproxen are safe pain relievers for most people. These may cause stomach irritation and bleeding or liver problems.
  • Narcotics can help in the short-term with acute pain. They should not be used for chronic pain. They have troublesome side effects, muddle your thinking and can be addictive.
  • Calcitonin is an osteoporosis drug sold under the brand names Miacalcin, Calcimar, or Fortical. Calcitonin may help relieve pain associated with bone fractures.
  • Antidepressant medication is sometimes prescribed to help people cope with chronic pain. These medications may be prescribed when other forms of pain relief have not helped.
Physical Approaches to Osteoporosis Pain

Doctors and therapists may also suggest physical therapies for controlling osteoporosis pain. These include:
  • Heat and ice. Both heat and cold can be effective at relieving pain. Warm showers or hot packs can ease stiff muscles. Cold can numb the painful area. Cold can also reduce swelling and inflammation.
  • Physical therapy. Osteoporosis pain may make it difficult for you to be physically active. However, inactivity may make pain worse by leaving you weakened. A physical therapist can work with you on a safe, effective exercise program.
  • Braces and supports. A back brace can relieve pain after a spinal fracture. A brace may also allow you to move around normally while the fracture is healing. But if you depend on the back brace too long, it can weaken your muscles. If you use a brace, begin exercising to strengthen back muscles as soon as your doctor says it is safe.
  • Acupuncture, acupressure, and massage therapy. These treatments all may help relieve pain and tension. If you have osteoporosis pain from spinal fractures, be sure that you talk with your doctor before seeing a massage therapist.
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http://www.kevinmd.com/blog/2011/06/doctors-letter-patient-newly-diagnosed-cancer.html
http://www.asco.org/ASCOv2/MultiMedi...=114&trackID=2

NICU 4.4 LB
Erythema Nodosum 85
Life-long Central Neurocytoma 4x5x6.5 cm 23 hrs 62090 semi-coma 10 d PT OT ST 30 d
3 Infertility tmts 99 > 3 u. fibroids > Pills
CN 3 GKRS 52301
IDC 1.2 cm Her2 +++ ER 5% R. Lmptmy SLNB+1 71703 6 FEC 33 R Tamoxifen
Recc IIB 2.5 cm Bi-L Mast 61407 2/9 nds PET
6 TCH Cellulitis - Lymphedema - compression sleeve & glove
H w x 4 MUGA 51 D, J 49 M
Diastasis recti
Tamoxifen B. scan
Irrtbl bowel 1'09
Colonoscopy 313
BRCA1 V1247I
hptc hemangioma
Vertigo
GI - > yogurt
hysterectomy/oophorectomy 011410
Exemestane 25 mg tab 102912 ~ 101016 stopped due to r. hip/l.thigh pain after long walk
DEXA 1/13
1-2016 lesions in liver largest 9mm & 1.3 cm onco. says not cancer.
3-11 Appendectomy - visually O.K., a lot of puss. Final path result - not cancer.
Start Vitamin D3 and Calcium supplement (600mg x2)
10-10 Stopped Exemestane due to r. hip/l.thigh pain OKed by Onco 11-08-2016
7-23-2018 9 mm groundglass nodule within the right lower lobe with indolent behavior. Due to possible adenocarcinoma, Recommend annual surveilence.
7-10-2019 CT to check lung nodule.
1-10-2020 8mm stable nodule on R Lung, two 6mm new ones on L Lung, a possible lymph node involvement in inter fissule.
"I WANT TO BE AN OUTRAGEOUS OLD WOMAN WHO NEVER GETS CALLED AN OLD LADY. I WANT TO GET SHARP EDGED & EARTH COLORED, TILL I FADE AWAY FROM PURE JOY." Irene from Tampa

Advocacy is a passion .. not a pastime - Joe
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Old 08-10-2010, 07:50 PM   #4
Laurel
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Re: aredia for osteopenia???

I take strontium, Vit D, calcium and magnesium for bone health. Google "Nan Fuchs" and read a bit on the strontium. Good luck!
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Dx'd w/multifocal DCIS/IDS 3/08
7mm invasive component
Partial mast. 5/08
Stage 1b, ER 80%, PR 90%, HER-2 6.9 on FISH
0/5 nodes
4 AC, 4 TH finished 9/08
Herceptin every 3 weeks. Finished 7/09
Tamoxifen 10/08. Switched to Femara 8/09
Bilat SPM w/reconstruction 10/08
Clinical Trial w/Clondronate 12/08
Stopped Clondronate--too hard on my gizzard!
Switched back to Tamoxifen due to tendon pain from Femara

15 Years NED
I think I just might hang around awhile....

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Old 03-06-2013, 01:49 AM   #5
Jackie07
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Re: aredia for osteopenia???

http://www.medpagetoday.com/Washingt...AGeneral/37676

FDA Panel Says 'No' to Osteoporosis Drug 'Calcitonin Salmon'...
__________________
Jackie07
http://www.kevinmd.com/blog/2011/06/doctors-letter-patient-newly-diagnosed-cancer.html
http://www.asco.org/ASCOv2/MultiMedi...=114&trackID=2

NICU 4.4 LB
Erythema Nodosum 85
Life-long Central Neurocytoma 4x5x6.5 cm 23 hrs 62090 semi-coma 10 d PT OT ST 30 d
3 Infertility tmts 99 > 3 u. fibroids > Pills
CN 3 GKRS 52301
IDC 1.2 cm Her2 +++ ER 5% R. Lmptmy SLNB+1 71703 6 FEC 33 R Tamoxifen
Recc IIB 2.5 cm Bi-L Mast 61407 2/9 nds PET
6 TCH Cellulitis - Lymphedema - compression sleeve & glove
H w x 4 MUGA 51 D, J 49 M
Diastasis recti
Tamoxifen B. scan
Irrtbl bowel 1'09
Colonoscopy 313
BRCA1 V1247I
hptc hemangioma
Vertigo
GI - > yogurt
hysterectomy/oophorectomy 011410
Exemestane 25 mg tab 102912 ~ 101016 stopped due to r. hip/l.thigh pain after long walk
DEXA 1/13
1-2016 lesions in liver largest 9mm & 1.3 cm onco. says not cancer.
3-11 Appendectomy - visually O.K., a lot of puss. Final path result - not cancer.
Start Vitamin D3 and Calcium supplement (600mg x2)
10-10 Stopped Exemestane due to r. hip/l.thigh pain OKed by Onco 11-08-2016
7-23-2018 9 mm groundglass nodule within the right lower lobe with indolent behavior. Due to possible adenocarcinoma, Recommend annual surveilence.
7-10-2019 CT to check lung nodule.
1-10-2020 8mm stable nodule on R Lung, two 6mm new ones on L Lung, a possible lymph node involvement in inter fissule.
"I WANT TO BE AN OUTRAGEOUS OLD WOMAN WHO NEVER GETS CALLED AN OLD LADY. I WANT TO GET SHARP EDGED & EARTH COLORED, TILL I FADE AWAY FROM PURE JOY." Irene from Tampa

Advocacy is a passion .. not a pastime - Joe

Last edited by Jackie07; 03-06-2013 at 01:53 AM..
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