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Old 02-18-2012, 01:25 AM   #1
kiwigirl
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Join Date: Jan 2010
Location: Matakana which is one hour north of Auckland, New Zealand.
Posts: 89
Re: OH what to do???

Does anyone know of pertsutinab cross into blood brain yet?
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Oct 2009 Masectomy 6 cm Tumor . Sentinal node biopsy , Node Positive . Her2 + er/pr -.
Nov 2009 X3 Taxane and Herceptin, X3 FEC
March 2010 25 Rads
March 2010 continued on Herception untill 16 Dec 2010
May 2010 Ultra Sound .... ALL CLEAR... NED
August 2010 started vaccine trial University of Washington
7th Dec 2010 finished vaccine trial
20th Dec 2010 Port removed
3rd Feb no longer ned brain mets
23r Feb start VMAT radiation
August 2011 two new mets to brain and others starting to grow again !!!!
August start tykerb and xeloda
Dec 1 MRI all small brain mets gone. Largest shrunk by 50% only three small ones to go 17mm,8mm,6mm. Mets on there way out. Yeah
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Old 02-18-2012, 02:34 AM   #2
Lani
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Re: OH what to do???

No, pertuzumab is a very large molecule, like herceptin and does not cross the blood-brain barrier normally.

If you have leptomeningeal metastasis, intrathecal herceptin has been tried (Courtney had it, I believe, among others). Boswellia serata has been tried for l-m mets as well. Try using the search function above for leptomeningeal metastasis I know I have posted several articles about treatments in the past

Good luck!
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