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Old 02-10-2013, 07:53 AM   #1
4angel
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lumpectomy vs. mastectomy?

I am looking for thoughts on the choice between having a lumpectomy vs. a mastectomy. I was diagnosed in Aug. 2012 with stage IV, having many mets to the liver but only one large primary in the right breast. It's very low, almost out of the actual breast tissue, but it was large. I finished 16 rounds of taxol, having both herceptin and perjeta every third week, also zometa as they have an area of bone they are watching. I will have the ovaries out early March as the breast area is Er+. All the Drs. involved feel removing the original site is a good idea, but two surgeons have each suggested different paths. The mass reduced by 1/2 during the first 8 rounds of chemo but has been stable since. If I choose a lumpectomy it will be a large area. If I choose the Mast. they are suggesting reconstruction though the surgeon and the oncologist may have different thoughts on this. Oncologist was worried about the need for future treatment and the reconstruction being "in the way" also the amount of stress it will add to my body as the liver is still in pretty poor shape. Any thoughts or directions to sites that might help me would be greatly appreciated. This is a very hard choice. ( my husband has had colon cancer twice, but his plan of action was always pretty straight forward, FYI he is doing very well...20 yrs since his first and 7 yrs. since his second) I had know idea there was so much not known about Breast cancer and which path works best. Thanks in advance for any thoughts you can share.
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Old 02-10-2013, 03:05 PM   #2
Becky
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Re: lumpectomy vs. mastectomy?

For you, or anyone for that matter, it is if there will be a good cosmetic result when you are done. If they have to take half your breast if having a lumpectomy, it will be difficult for you and you will probably have to stuff your bra with tissues for the breasts to match. If this is the case, masectomy would be a better option. If you didn't get reconstruction, you would at least have a prostetic that will match the remaining breast. So, your question can only be answered by your surgical team and how much breast has to be removed in order to remove all the cancer. And after doing so, what amount of breast will be left.
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Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
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Old 02-11-2013, 05:32 AM   #3
Jackie07
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Re: lumpectomy vs. mastectomy?

Ann Surg. 2012 Jun;255(6):1151-7. doi: 10.1097/SLA.0b013e31824f9769.
Evaluating the feasibility of extended partial mastectomy and immediate reduction mammoplasty reconstruction as an alternative to mastectomy.

Chang EI, Peled AW, Foster RD, Lin C, Zeidler KR, Ewing CA, Alvarado M, Hwang ES, Esserman LJ.
Source

Division of Plastic and Reconstructive Surgery, Department of Surgery, University of California, San Francisco, CA, USA.

Abstract

OBJECTIVES:

To assess the efficacy of using concurrent partial mastectomy and reduction mammoplasty for resection of a wide range of tumor sizes and compare oncologic outcomes and postoperative complications on the basis of tumor size.
BACKGROUND:

Although tumor size greater than 4 cm has been considered an indication for undergoing a mastectomy, this dictum may not apply in women with breast hypertrophy, where the ratio of tumor size to breast size may still permit breast conservation. We wished to evaluate whether an approach combining partial mastectomy with reduction mammoplasty could provide a safe oncologic procedure with immediate breast reconstruction that could technically be applied even for large (>4 cm) lesions.
METHODS:

A retrospective review of all patients undergoing partial mastectomy and concurrent reduction mammoplasty performed at our institution from 2000 to 2009. Clinical characteristics at presentation, pathologic data, and follow-up data were collected and analyzed.
RESULTS:

Eighty-five consecutive simultaneous partial mastectomy/reduction mammoplasty procedures were performed in 79 patients. Average tumor size was 2.8 cm for ductal carcinoma in situ (0.05-17.0 cm), 2.4 cm for invasive ductal carcinoma (IDC) (0.2-8.9 cm), 3.5 cm for lobular carcinoma (1.6-8.0 cm), and 5.7 cm for phyllodes tumors (3.7-7.6 cm). Twenty-five of 85 tumors (29.4%) were larger than 4 cm. Distribution for stage 0, I, II, III, and IV disease was 15, 12, 35, 19, and 2 tumors respectively, with an additional 2 phyllodes tumors. Median follow-up was 39 months (10-130 months). Seventy-five patients (94.9%) achieved successful breast conservation, whereas 4 patients (5.1%) went on to completion mastectomy. Thirteen patients (16.4%) required 1 reexcision to achieve clear margins, and 2 (2.5%) required multiple reexcisions. Two patients had a local recurrence during the follow-up period, one of whom underwent reexcision and the other underwent mastectomy. The overall complication rate was 14.1%, which included 4 major complications (4.7%) requiring an unplanned return to the operating room and need for hospital readmission, and 8 minor wound-related complications (9.4%). Neither recurrence nor complication rates were increased in patients with tumors greater than 4 cm when compared with tumors less than or equal to 4 cm.
CONCLUSIONS:

A partial mastectomy with concurrent reduction mammoplasty technique is a viable option for breast conservation even for larger tumors, combining a safe oncologic procedure with excellent cosmesis. A combined effort between breast surgeons and reconstructive surgeons has a high probability of success with low recurrence rates. In carefully selected patients, this approach may be preferable to mastecomy and breast reconstruction, particularly when postmastectomy radiation therapy is anticipated.
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Old 02-11-2013, 06:06 AM   #4
linn65
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Re: lumpectomy vs. mastectomy?

If it was your daughter or sister what would you tell her??? I was unable to do my reconstruction right away because just finishing chemo and 3 weeks later doing the masectomy they felt it would be too hard for my body to go thru all at once. Personally, I would do the masectomy and not worry about trying to match 1 breast and the other making it whole...Now, that I only have 1 breast I can not wait to remove the other one when I have reconstruction done, so I don't need to worry about them matching. At first I was like I don't know if I want the other breast off but now that I am going through trying to match the real one with a prosthetic it is a pain, so I rather just have two fake ones! I am like you I had no idea that Breast cancer was so complicated but it sure is!!!
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IDC breast cancer
7/2012 diagnosed with multiple solid lesions
7/20/12 biopsy done. ER+ 30 PR -, HER+++,k167 80% Grade 2
9/2012 biopsy on lymph node - showed malignant

9/2012 Pre-adjunctive TCH chemo.

12/6/12 MRI after Pre-adj.
Results: Modest Decrease in size of left breast malignancy As well as the associated satellite lesions and auxiliary Adenopathy compared to prior study. Doctors hoped for better but good response it didn't grow.

12/18/2012 left masectomy with axillary nodes
Size 3.2 CM, Nottingham score 9/9
Grade 3, no evidence of in situ carcinoma
Areas of angiolymphatic are identified
Carcinoma is 0.5 cm from inked deep
Margin of excision
Attached axillary lymph nodes: metastatic
Carcinoma in 6 of 8 nodes.
Size of largest node 1.5 cm
Extracapsular
ER + 73%, PR+2%, HER2+

2/27/13 6 weeks of IMRT radiation finished

2/2013 Started on Tamoxifan 5 years.

8/2013 will take last Herceptin, 17 treatments total every 3 weeks.

BRCA1 & BRAC2 - Negative

August 28, 2013 DIEP flap on the left breast.
February 2014 Nip & Tuck
March 14, 2014 nipple reconstruction and removed port.
August 14, 2014 lump in lymph nodes under arm and above clavicle. Stage IV
August 28, 2014 herceptin And projeta starting and port put back in.

3/18/15 stopped arimidex.
3/18/15 progression....Tdm1
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Old 02-11-2013, 08:12 AM   #5
Lauriesh
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Re: lumpectomy vs. mastectomy?

From a stage 4 perspective, I would be concerned about how the surgery could affect future treatment . After the mast, you would have to wait at least 6 weeks to start chemo again. It could be longer if there are any complications. If your liver got worse during this time, what options would you have.
I think I would take the advice of your onc.


Laurie
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4 AC
12 taxol/Herceptin
Year of Herceptin
liver mets- July-2010
7 taxotere/Herceptin
RFA- Feb.2011
NED
U of Wa vaccine trial-oct 2011-Feb 2012
Herceptin/tykerb
Ned - 2 1/2 years
Herceptin & perjeta
Ned 3 years
Herceptin- reducing treatments , due to s/e, to 5-6 a year
NED- 3 1/2 years
Ned - 4 years
2/15- stopped herceptin - on no treatment
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Old 02-11-2013, 01:47 PM   #6
tricia keegan
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Re: lumpectomy vs. mastectomy?

I'm not stage iv but did have a lumpectomy and have a small half prosthesis which tucks in to my bra and both breasts now look identical so for me, I'd say go with the lumpectomy and I have had no regrets. Try googling Dr Susan Love where you may get more info on this issue.
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Dx July '05 IDC 1.9cm Triple positive 3/9 nodes positive
A/C X 4 ..Taxol/Herceptin x 12 wks then herceptin 1 yr
Rads x 36 ..oophorectomy August '06
Currently taking Arimidex..
June 2011 osteopenia/ zometa x1 yearly- stopped Zometa 2015 as Dexa show normal bone density.
Stopped Arimidex July 2014- Restarted Arimidex 2015 for a further two years on the advice of my Onc.
2014 Normal Dexa scan
2018 Mammo all clear, still NED!
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Old 02-14-2013, 01:00 AM   #7
Joanne S
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Re: lumpectomy vs. mastectomy?

It's definitely a difficult personal decision- lumpectomy, mastectomy or double mastectomy? All the responses above provide great suggestions.

Six weeks after I completed my treatments, I had a double mastectomy. I didn't want one side to be different than the other side; additionally, I didn't want to have future concerns or worries about breast lumps, mammograms, etc. --- lumpectomy was not an option I even considered--- but that's just me. I felt that if I only had 1/2 or one breast removed, I wouldn't have the option to go bra-less, and did not want to go bra-less lopsided. I have prosthetic boobs and mastectomy bras, but I never wear them as they are very uncomfortable for me (special occassions only). However, many other women that have them are quite comfortable and don't have any issues.

As mentioned above by Laurie, I would focus and make getting chemo and all the necessary treatments done first before having surgery.

Allow yourself plenty of time to educate yourself on all the available surgical and reconstruction options so you can make the best decision option for you.

Wishing you the best in the treatment, Joanne
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Aug06...Dx Age 50, IDC Left Breast, 6+/16 lymph nodes, Stg 3, ER+/PR+/HER2+
Sep06-Jan07...Mediport. Chemo: AC x 4, T x 4
Dec06-Nov07...Herceptin
Feb12,2007...Surg MRM Left & SM Right, reconstruct w/expanders
Mar07-Jun07...Saline Exp
Jun07...Start Tamoxifen
Jun07-Aug07...Rad x 25
Jun07-Oct07...Persistent fevers-unknown origin
Jun07-Nov07...PT for Severe PMPS & Capsular Contracture
Nov07...Surg Capsulectomy, Gel Implants, PMPS pain gone instantly.
Feb08...NED 1st CANCERVERSARY!!!!!
Feb08...2 months post surgery Caps Cont again :(
Mar08...Stop Tamoxifen. Start Arimidex.
Apr08...Sudden high fever, Hosp ICU 10 days, staph infect, emerg surg, implants removed. Outpt IVantibiotics Daily x 6 weeks
Feb11...NED 5th CANCERVERSARY!!!!!
Feb12...NED 6th CANCERVERSARY!!!!!
Aug12...Spotting. Surg=D&C
Sep12...STAGE IV = RARE BC METS TO UTERUS ILC ER+/PR+/HER2-Negative) (Different BC than originally diagnosed = IDC ER+/PR+/HER2+).
Sep12...Stop Arimidex. Start Afinitor & Aromasin.
Jan13...MRI = no progression no reduction
Apr13...Progression. Stop Afinitor & Aromasin.
Apr13...Start Chemo: Taxol & Carboplatin.
Nov13...Scans & Pelvic 95+% Reduction. Nueropathy>Stop chemo start Fareston.
Jan14...PET scan = no progression stable.
May14...Pelvic > Bleeding & cramps. TMs up.
May14...PET scan = uterine progression :(
May14...Stop Fareston. Start Chemo: Xeloda.



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