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Old 06-01-2008, 11:57 AM   #1
Hopeful
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Estrogen Paradox

http://www.asco.org/ASCO/Meetings/AS...+Breast+Cancer

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Old 06-01-2008, 03:43 PM   #2
R.B.
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Thanks for posting.

AA has always been asking questions about this.

It is noted that there is intervention in the lipid (fat) pathways by oestrogen treatments.

Oestrogen promotes fat conversion pathways.

Lack of long chain Omega 3s has been associated with higher risk of BC.

Fascinating implications from the little I try to understand.

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Old 06-01-2008, 10:49 PM   #3
harrie
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Hopeful, very interesting article. YRS ago when I was on Tamoxifen, I remember reading or hearing that 5 yrs max was recommended because after that it may actually promote breast tumors rather then inhibit it. This was a long time ago and maybe it was a theory rather then fact.
Well one thing, if a person is on AI's long enough to experience the changing of the configuration of the cancer cell in phase II, and the indication is to be put on estrogen therapy, well right there should be our solution for those suffering from vaginal atrophy! (lol!)
__________________
*** MARYANNE *** aka HARRIECANARIE

1993: right side DCIS, lumpectomy, rads
1999: left side DCIS, lumpectomy, rads, tamoxifen

2006:
BRCA 2 positive
Stage I, invasive DCIS (6mm x 5mm)
Grade: intermediate
sentinal node biopsy: neg
HER2/neu amplified 4.7
ER+/PR+
TOPO II neg
Oncotype dx 20
Bilat mastectomy with DIEP flap reconstruction
oophorectomy

2007:
6 cycles TCH (taxotere, carboplatin, herceptin)
finished 1 yr herceptin 05/07
Arimidex, stopped after almost 1 yr
Femara
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Old 06-02-2008, 06:39 AM   #4
Hopeful
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Harrie, I actually thought the same thing.

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