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08-31-2010, 10:36 PM
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#1
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Senior Member
Join Date: Oct 2005
Location: New Jersey
Posts: 3,154
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Dr. Edith Perez give great stats....
http://news.cancerconnect.com/sabcs-...breast-cancer/
While this was taped from 2009 it is still worthy of viewing and hearing good news re: the stat reports.
__________________
Stage 1, Grade 1, 3/30/05
Lumpectomy 4/15/05 - 6MM IDC
Node Neg. (Sentinel node)
ER+ 90% / PR-, Her2+++ by FISH
Ki-67 40%
Arimidex 5/05
Radiation 32 trt, 5/30/05
Oncotype DX test 4/17/06, 31% high risk
TOPO 11 neg. 4/06
Stopped Arimidex 5/06
TCH 5/06, 6 treatments
Herceptin 5/06 - for 1 yr.
9/06 Completed chemo
Started Femara Sept. 2006
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09-01-2010, 03:39 AM
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#2
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Senior Member
Join Date: Sep 2005
Location: france
Posts: 1,648
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Re: Dr. Edith Perez give great stats....
yes sounds good but it didn't state whether the cancer was just in the breast or in the nodes or metastatic or did I miss that?
sarah
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09-01-2010, 05:08 AM
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#3
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Senior Member
Join Date: Aug 2003
Location: Morris, IL
Posts: 3,507
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Re: Dr. Edith Perez give great stats....
Jean
I went to her seminar last year in San Antonio....I could listen to her talk for hours....thanks for posting!
__________________
"Be kinder than necessary, for everyone you meet is fighting some kind of battle."
Hugs & Blessings
Sheila
Diagnosed at age 49.99999 2/21/2002 via Mammography (Calcifications)
Core Biopsy 2/22/02
L. Mastectomy 2/25/2002
Stage 1, 0.7cm IDC, Node Neg from 19 nodes Her2+++ ER PR Neg
6/2003 Reconstruction W/ Tissue Expander, Silicone Implant
9/2003 Stage IV with Mets to Supraclavicular nodes
9/2003 Began Herceptin every 3 weeks
3/2006 Xeloda 2500mg/Herceptin for recurrence to neck nodes
3/2007 Added back the Xeloda with Herceptin for continued mets to nodes
5/2007 Taken Off Xeloda, no longer working
6/14/07 Taxol/Herceptin/Avastin
3/26 - 5/28/08 Taxol Holiday Whopeeeeeeeee
5/29 2008 Back on Taxol w Herceptin q 2 weeks
4/2009 Progression on Taxol & Paralyzed L Vocal Cord from Nodes Pressing on Nerve
5/2009 Begin Rx with Navelbine/Herceptin
11/09 Progression on Navelbine
Fought for and started Tykerb/Herceptin...nodes are melting!!!!!
2/2010 Back to Avastin/Herceptin
5/2010 Switched to Metronomic Chemo with Herceptin...Cytoxan and Methotrexate
Pericardial Window Surgery to Drain Pericardial Effusion
7/2010 Back to walking a mile a day...YEAH!!!!
9/2010 Nodes are back with a vengence in neck
Qualified for TDM-1 EAP
10/6/10 Begin my miracle drug, TDM-1
Mixed response, shrinking internal nodes, progression skin mets after 3 treatments
12/6/10 Started Halaven (Eribulen) /Herceptin excellent results in 2 treatments
2/2011 I CELEBRATE my 9 YEAR MARK!!!!!!!!!!!!!
7/5/11 begin Gemzar /Herceptin for node progression
2/8/2012 Gemzar stopped, Continue Herceptin
2/20/2012 Begin Tomo Radiation to Neck Nodes
2/21/2012 I CELEBRATE 10 YEARS
5/12/2012 BeganTaxotere/ Herceptin is my next miracle for new node progression
6/28/12 Stopped Taxotere due to pregression, Started Perjeta/Herceptin
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09-01-2010, 06:27 AM
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#4
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Senior Member
Join Date: Apr 2008
Posts: 1,477
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Re: Dr. Edith Perez give great stats....
Jean,
Thanks much for posting.
Karen
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09-01-2010, 07:02 AM
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#5
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Senior Member
Join Date: Mar 2009
Posts: 508
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Re: Dr. Edith Perez give great stats....
My sis is about to finish her treatment---one more Herceptin then port removal. It was good to see the film clip and be reminded of the encouraging news about targeted therapy! Thanks, Jean.
Barb A.
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09-01-2010, 09:03 AM
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#6
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Senior Member
Join Date: Sep 2005
Location: Alaska
Posts: 2,018
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Re: Dr. Edith Perez give great stats....
It is an interesting link. As it indicates, the vast majority of early stage breast cancer patients do survive to 10 years without any recurrence without chemotherapy. But how sad it is that because the trials focused on including chemotherapy, we don't have the data to show how effective trastuzumab alone might have been for this group instead.
A.A.
__________________
Dx 2002 age 51
bc for granny, aunt, cousin, sister, mother.
ER+/PR+/HER2+++, grade 3
IDC 1.9 cm, some DCIS, Stage 1, Grade 3
Lumpectomy, CAFx6 (no blood boosters), IMRT rads, 1 3/4 yr tamoxifen
Rads necrosis
BRCA 1 & 2 negative
Trials: Early detection OVCA; 2004 low-dose testosterone for bc survivors
Diet: Primarily vegetarian organic; metformin (no diabetes), vitamin D3
Exercise: 7 days a week, 1 hr/day
No trastuzumab, no taxane, no AI
NED
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09-01-2010, 09:22 AM
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#7
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Senior Member
Join Date: Oct 2005
Location: New Jersey
Posts: 3,154
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Re: Dr. Edith Perez give great stats....
Hi Sarah,
The nature of this study was for early stage. I will do some searching and see if there is any current information on later stage study with stats. We do know that many later stage patients are surviving while on herceptin and even after stopping treatment.
Andi, who was on herceptin for over 12 yrs. and now is off herceptin and still NED, and Christine, are just two that quickly come to mind. Also keep in mind Sarah, that even when dx. in the later stages each case is different and great strides are being made in that area also.
Barb, wishing your sister the best as she finishes her treatment. These clips give all having treatment encouraging uplift as they complete their treatment.
So many women feel worried when the herceptin treatment is concluded. Often times after being on herceptin for the year women will say - "I almost don't want to stop, will the cancer return" at least this will offer encouragment to many that we are making strides - the stats show this, as Dr. Perez states. This study is showing our treatments are getting better.
Sheila - I know she is just wonderful - very encouraging
and a true fighter for all of us. She was doing another study about five years ago when I was first dx. and I reached out to her and she got on the phone and discussed my questions. She was a great help to me in those early days of dx. Very dedicated and committed doctor for us. (love you Sheila)..Glad you are feeing better.
__________________
Stage 1, Grade 1, 3/30/05
Lumpectomy 4/15/05 - 6MM IDC
Node Neg. (Sentinel node)
ER+ 90% / PR-, Her2+++ by FISH
Ki-67 40%
Arimidex 5/05
Radiation 32 trt, 5/30/05
Oncotype DX test 4/17/06, 31% high risk
TOPO 11 neg. 4/06
Stopped Arimidex 5/06
TCH 5/06, 6 treatments
Herceptin 5/06 - for 1 yr.
9/06 Completed chemo
Started Femara Sept. 2006
Last edited by Jean; 09-01-2010 at 09:42 AM..
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09-01-2010, 10:07 AM
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#8
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Senior Member
Join Date: Oct 2005
Location: New Jersey
Posts: 3,154
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Re: Dr. Edith Perez give great stats....
Sarah,
I did find the following article which explains some very promising techniques in treatment for the later stage patient. Especially interesting is the study on vaccines at the UNC. The vaccine is not to prevent but to increase the bodies immune system to fight the disease. This is especially useful for those who are at a later stage and not NED - and a big leap - being customized for the patient.
Jean
http://www.webmd.com/breast-cancer/f...ancer-patients
__________________
Stage 1, Grade 1, 3/30/05
Lumpectomy 4/15/05 - 6MM IDC
Node Neg. (Sentinel node)
ER+ 90% / PR-, Her2+++ by FISH
Ki-67 40%
Arimidex 5/05
Radiation 32 trt, 5/30/05
Oncotype DX test 4/17/06, 31% high risk
TOPO 11 neg. 4/06
Stopped Arimidex 5/06
TCH 5/06, 6 treatments
Herceptin 5/06 - for 1 yr.
9/06 Completed chemo
Started Femara Sept. 2006
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09-01-2010, 11:52 AM
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#9
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Senior Member
Join Date: Jun 2006
Location: San Antonio, TX
Posts: 2,357
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Re: Dr. Edith Perez give great stats....
Jean, I've so very glad that you are YOU! ma
__________________
MA in TX.
Grateful for each and every day....
Diag. 12/05 at age 60
Stage II, Grade 3, 4.5 cm primary tumor
ER/PR- Her2 +3 strongly positive
Her2 by FISH 7.7 amplified
vascular invasion
Ki67 20% borderline
Jan - March '06 Taxotere/Adriamycin X 3 to try to shrink tumor - it grew
April '06 Rt Modified Radical Mas, 7 of 9 nodes positive
April - Aug. '06 Herceptin/Taxol/Carboplatin X 8 (dose dense)
Sept - Dec. '06 Navelbine/Herceptin x 8 (dose dense)
Radiation & Herceptin Jan. 22 - March 1, 2007
Finished Herceptin Dec. 10 '08! One extra year.
Port removed August, 2012.
8 1/2 years since diagnosis! 5 1/2 Years NED!
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05-06-2011, 07:33 AM
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#10
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Senior Member
Join Date: Sep 2005
Location: france
Posts: 1,648
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Re: Dr. Edith Perez give great stats....
Thanks Jean.
It's all very interesting.
health and happiness
love sarah
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05-06-2011, 05:15 PM
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#11
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Senior Member
Join Date: Nov 2005
Location: Ireland
Posts: 3,463
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Re: Dr. Edith Perez give great stats....
Thanks Jean, its good to get some stats on how herceptin has really helped us early stagers!
__________________
Tricia
Dx July '05 IDC 1.9cm Triple positive 3/9 nodes positive
A/C X 4 ..Taxol/Herceptin x 12 wks then herceptin 1 yr
Rads x 36 ..oophorectomy August '06
Currently taking Arimidex..
June 2011 osteopenia/ zometa x1 yearly- stopped Zometa 2015 as Dexa show normal bone density.
Stopped Arimidex July 2014- Restarted Arimidex 2015 for a further two years on the advice of my Onc.
2014 Normal Dexa scan
2018 Mammo all clear, still NED!
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