Clinical trial targets breast cancer cells by injecting trastuzumab directly into the

[News]

In two to five percent of women with breast cancer, tumor cells migrate into the spinal fluid invading the tissue surrounding the brain and spinal cord called the meninges. While a rare complication, the condition is challenging because there is no agreed-upon standard of treatment, leaving little hope for patients affected. Northwestern Medicine- researchers are currently examining a novel approach to delivering an FDA approved drug that they hope will advance research for this type of cancer and lead to discoveries that may improve outcomes in the future.

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[Rolepaul]

This trial was used as the basis for treatment for my wife. We felt the dosage was a little lower than was effective in other literature so we went to his highest dose of 40 mg for four weeks and doubled that to 80 mg weekly for 8 weeks, and now are on every two weeks 80 mg. I can tell you that Dr. Raizer has 10 mg, 20 mg, 30 mg, and 40 mg arms of this trial. This is a very worthwhile trial and will lead to additional work, we just felt like we could not wait. I respect the work, but if you have brain/spine involvement you cannot wait for higher dosage levels to be explored. Time to get to the right level of treatment as soon as possible. Excellent work by Dr. Raizer.

['lizbeth]

So relieved that Dr. Raizer is working on a treatment for brain/spine mets.

Grateful to have you share your experience.