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Old 06-25-2008, 04:50 AM   #1
Laurieanne
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Smile Taxotere, Cytoxin

Hi guys,

I'm wondering if anyone could tell me their experience with Taxotere and cytoxin. My doctor told me yesterday
that will be my chemo. Also herceptin for at least a year.

Thanks, Laurie
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Old 06-28-2008, 11:35 PM   #2
Chelee
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Hi Laurie, I didn't have cytoxin...however I did have taxotere & herceptin. But I'm sure someone here had that exact combo of chemo. There's been alot of posts lately so yours got pushed down quickly. I thought I would "bump" it back up so that you will get some replies.

I can tell you one thing in advanced...the herceptin is usually very well tolerated by most women. You will usually have a muga or echo test every 3 months to keep an eye on your heart so don't let that stress you out. The taxotere can give you a nasty taste in your mouth, and cause a few aches and pains but believe me you can do it. Once you get the taxotere and cytoxin behind you the herceptin will be a cake walk. Hang in there I am sure others will reply.

Chelee
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DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes.
Rt. MRM on 1-3-06 -- No Rads due to compromised lungs.
Chemo started 2-7-06 -- TCH - - Finished 6-12-06
Finished yr of wkly herceptin 3-19-07
3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07
9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV.
9-28-09 Loading dose of Herceptin & started Zometa
9-29-09 Power Port Placement
10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head.
11-19-09 RT. Femur surgery - Rod placed
12-7-09 Navelbine added to Herceptin/Zometa.
3-23-10 Ten days of rads to RT femur. Completed.
4-05-10 Quit Navelbine--Herceptin/Zometa alone.
5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy.
Results to FISH was unsuccessful--this happens less then 2% of the time.
7-7-10 Recurrence to RT axilla again. Back to UCLA for options.
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Old 06-29-2008, 07:56 AM   #3
CindyE
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Hello,
I'm on Taxotere, Cytoxan, and Herceptin. I've been able to tolerate it pretty well with the pre-meds and a few post-med anti nausea pills. I've had two rounds and was just down for about 4-5 days both times. Never got sick but just felt lousy kinda like the flu.

Hope all goes well for you. Check in once you have had your treatment so we can keep in touch. It's always helpful to compare notes on this things.

Take care,

Cindy
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Cindy

L/IDC, 1.2 cm, Stage 1, Her2+, ER+/PR+ at age 48
4/15/2008 Lumpectomy + sentinel node biopsy
Margins neg and Nodes neg (2 tested)
MUGA score 55 on 5/6/2008

Treatment starting 05/08/2008:
Chemo 4 cycles, 3 weeks apart with Taxotere & Cytoxan - Chemo - Done 7/24/2008!
Herceptin for 1 year
Radiation starting in 9/2008
MUGA score 61.9 on 9/04/2008
33 Rads with boost - Done 10/13/2008
MUGA score 58 on 12/01/2008
MUGA score 59 on 3/16/2009
Herceptin for 1 year - Done 4/27/2009
MUGA score 64 on 6/22/2009
All scans - NED 6/24/2009
MRI - NED 11/10/2009
All scans - Still NED 8/25/2011
Still NED 2017!



I am calling this my pink journey
Follow my journey into the pink at my blog here

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Old 06-29-2008, 08:20 AM   #4
LOPSIDED
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I Had 12 Taxotere Treatments And I Had Some Fatigue And Around Treatment 8 My Eyes Started Tearing.
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SHEILA (45)
09/2005--BREAST CANCER/8 POS NODES --A/C, MASTECTOMY,TAXOTERE, RADS, TAMOXIFEN,HERCEPTIN
02/2007--B/C METS TO OVARIES--HYSTERECTOMY, FASLODEX
12/2007--ENLARGING LYMPH NODES IN ABDOMEN--IXEMPRA, THEN TYKERB
08/2008--COLON TUMOR--A/C AGAIN,
12/2008--ABDOMEN TUMOR--AVASTIN/NAVELBINE FEMARA
05/2009--MET TO SPINE (L2) RADS
CURRENT TREATMENT
07/2009- START ZOMETA MONTHLY, XELODA & ABRAXANE......SURVIVING THE BEST I CAN
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Old 06-30-2008, 11:56 AM   #5
Joan M
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Do you have to take Decadron with Taxotere? I had to take it when I had Taxol.
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Diagnosed stage 2b in July 2003 (2.3 cm, HER2+, ER-/PR-, 7+ nodes). Treated with mastectomy (with immediate DIEP flap reconstruction), AC + T/Herceptin (off label). Cancer advanced to lung in Jan. 2007 (1 cm nodule). Started Herceptin every 3 weeks. Lung wedge resection April 2007. Cancer recurred in lung April 2008. RFA of lung in August 2008. 2nd annual brain MRI in Oct. 2008 discovered 2.6 cm cystic tumor in left frontal lobe. Craniotomy Oct. 2008 (ER-/PR-/HER2-) followed by targeted radiation (IMRT). Coughing up blood Feb. 2009. Thoractomy July 2009 to cut out fungal ball of common soil fungus (aspergillus) that grew in the RFA cavity (most likely inhaled while gardening). No cancer, only fungus. Removal of tiny melanoma from upper left arm, plus sentinel lymph node biopsy in Feb. 2016. Guardant Health liquid biopsy in Feb. 2016 showed mutations in 4 subtypes of TP53. Repeat of Guardant Health biopsy in Jana. 2021 showed 3 TP53 mutations, BRCA1 mutation and CHEK2 mutation. Invitae genetic testing showed negative for all of these. Living with MBC since 2007. Stopped Herceptin Hylecta (injection) treatment in March 2020. Recent 2021 annual CT of chest, abdomen and pelvis and annual brain MRI showed NED. Praying for NED forever!!
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Old 06-30-2008, 03:33 PM   #6
Laurieanne
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Thanks everybody,
I'm not sure when I'll start chemo. I have a bilateral mastectomy on July 14th. So I guess it depends on how well I heal. I'm having immediate implant reconstruction. The closer it gets the more nervous I am, but I'm anxious to get it over with.
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Old 06-30-2008, 07:16 PM   #7
CindyE
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Yes, I get Decadron before my Taxotere and Cytoxan. I declined the two pills for the two days after chemo as I just didn't want all the extra steroids. I just don't think I need them or the extra stuff that comes with the pills.
__________________
Cindy

L/IDC, 1.2 cm, Stage 1, Her2+, ER+/PR+ at age 48
4/15/2008 Lumpectomy + sentinel node biopsy
Margins neg and Nodes neg (2 tested)
MUGA score 55 on 5/6/2008

Treatment starting 05/08/2008:
Chemo 4 cycles, 3 weeks apart with Taxotere & Cytoxan - Chemo - Done 7/24/2008!
Herceptin for 1 year
Radiation starting in 9/2008
MUGA score 61.9 on 9/04/2008
33 Rads with boost - Done 10/13/2008
MUGA score 58 on 12/01/2008
MUGA score 59 on 3/16/2009
Herceptin for 1 year - Done 4/27/2009
MUGA score 64 on 6/22/2009
All scans - NED 6/24/2009
MRI - NED 11/10/2009
All scans - Still NED 8/25/2011
Still NED 2017!



I am calling this my pink journey
Follow my journey into the pink at my blog here

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