Intrathecal (IT) Herceptin (Trastuzumab) for brain mets (Leptomeningeal Metastases)

marvass · 06-10-2015, 10:34 AM

MRI of yesterday:

All three spots gone and none new seen, thank God.

We have done 10 IT herceptin till now each of 150mg herceptin, and 50mg hydrocortisone, each shot every 10/11 days, i.e. 2 times every three weeks. We also did 6mg/kg IV herceptine every three weeks.

Will continue same treatment for another 3 months, and MRI again.

Mario

thinkpositive · 06-10-2015, 10:40 AM

Mario,

Thanks for sharing your good news! Looks like this treatment is working. I'm very happy for you.

Take Care,
Brenda

phil · 06-10-2015, 10:52 AM

ASCO last week talked about a promising new tx for her2 , w/ brain mets. a genetic drug - ON380 ( sp. ? ) added to kadcyla. phase I had good results in 8 out of 8 pts who got this combo.