Hi Cathy,
Yes, I did have genetic testing done. 23andMe used to offer a tempting discount on DNA Day, and I was curious, so I sent away for my test tube. I also had my adult daughter tested, which made the results even more interesting. I believe the current cost is a flat rate is $299.
I do use it to help me choose the supplements I need to compensate for genetic shortfalls, although that wasn't part of my plan when I ordered the kit.
23andMe does offer a certain amount of information about diseases, conditions and traits, but I've found it to be limited. For example, it led me to believe that I have a lower risk of breast cancer than the average woman. You can imagine my surprise when my gynecologist found the lump.
To compensate for 23andMe's reporting deficiency, I use my raw data file with SNPedia's Promethease. I'm also registered on sites like opensnp.org (where I've uploaded my raw data file for public use and viewing), and I spend a lot of time rooting around in obscure gene databases. As it turns out, although I'm BRCA1 and 2 negative, I have other genes to indicate I'm at higher risk.
As to Val158Met, there's a ton of information, including the factoid about modafinil, on SNPedia:
http://snpedia.com/index.php/Rs4680
Hybrid Mode
