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Old 02-22-2012, 04:16 PM   #1
NanaJoni
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Re: Herceptin as monotherapy - no chemo

Nana (I'm a Nana, too) - I did Herceptin every week while I was doing TCH. It was TCH every third week with the Herceptin the two weeks in between. After I stopped the TCH, I went to Herceptin every three weeks for most of the next year. This seems to be a standard protocol for many.
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3/01/10: found lump in rt.breast
3/12/10: mammogram/ultrasnd/biopsy-invasive bc & DCIS; 2 tumors (2cm er-/pr-/HER2-& 1.8 cm er-/pr-/HER2+); grade 3;poorly differentiated
3/24/10:sent.node biopsy clear
3/31/10:bi-lateral mx.;atypical ductal hyperplasia-lft side
4/21/10:wound revision-infection/scarring 4/28/10:seromas both sides
5/21/10:port installed,TCH chemo (6 x 3 wks); Herc,-1yr; 33 rad tx after chemo
07/2010: port not working-2nd port didnt'work;3rd port opposite side.
07/2010: 2 weeks after 3rd port surgery, threw 3 pulm. emboli-IVC filter installed; warfarin
08/2010: hospitalizations w/3 of chemos; decision to stop after 4th-on to radiation in Oct 2010;Herc cont.
12/03/2010 - finished 33 rads Hooray!! cont. Herc. every 3 wks
4/2011 - pneumonia ??? Nope-radiation pneumonitis. No more Herc.
5/2011 - NED!!! port out.
8/2011 - clean PET & CT scans.Still NED
7/2012 - Still NED/very blessed.
2/2013 - 6 mos checkup-all clear. CA2729 down frm 13 to 11.
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Old 02-22-2012, 09:52 PM   #2
Jackie07
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Re: Herceptin as monotherapy - no chemo

Nana2three,

When the MUGA score showed decline after I had completed 18 weeks of TCH in 2007, I was given the Herceptin weekly instead of every three weeks. My understanding is that with a lower weekly dose, the potential of further heart damage is reduced.

I have a congenital problem called 'Mitral Valve prolapse', so there's not much I could do to improve my heart function. Several members have reported both daily exercise and certain supplements (enalapril?) helped them finish the one year Herceptin.

Evebarry also has just begun her treatment with Herceptin as monotherapy. She looks very young in her picture, but she is closer to your age group than mine. Perhaps y'al can compare notes during treatment? (I think she's also getting it every 3 weeks.)
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Last edited by Jackie07; 02-23-2012 at 09:29 PM..
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