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Old 03-19-2010, 08:24 PM   #1
LoriG
Senior Member
 
Join Date: Jan 2010
Posts: 28
Re: Tykerb/Xeloda, side effects??
Just an update...went to MDA this week. My PET not only showed not evidence of mets but also no evidence of active cancer in the breast! I was SHOCKED. My ultraound confirmed scar tissue in the breast but does not look like active disease. I am FINALLY ready for surgery!! I realize there is likely still a decent amount of microscopic cancer in the breast, but this is a hige change from my PET 3 months ago which showed a ton of FDG activity in the breast.

Anyway, just thought I would share.

Thanks, everyone! Ellie, hope your upcoming scans go well!
__________________
Lori, age 33
*IBC (ER+,PR-,Her2+) on right diagnosed 8/09 with metastatic lymph node left axilla (Er-,PR-,Her2+) vs possible bilateral breast cancer
*A/C x4
*Taxol x4 with weekly herceptin
*Breast MRI 12/09- no improvement
*PET scan 12/09- no evidence of mets
*Tykerb/Xeloda 12/09
*Bilateral MRM 4/10
*Twice daily rads to both chest walls and both axillas 5/10-6/10
*9/10 PET/CT- NED
*Tykerb/Xeloda until 12/10
*Tykerb and Tamoxifen 12/10-current. Bye bye Xeloda
*2/11- malignant pleural effusions bilaterally (likely lymphangitic lung mets) and skin mets
Herceptin and Ixempra
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Old 03-20-2010, 03:34 AM   #2
VirginiaGirl
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Join Date: Oct 2006
Location: Fredericksburg, VA
Posts: 93
Re: Tykerb/Xeloda, side effects??
Lori,
What AWESOME news! I can imagine how you're having a hard time wrapping your brain around it! Very cool! If there's no tumor left, what is the surgery? Mastectomy? Congratulations again, and may we all have such stellar results from this combo!
__________________
Liz
3/05 Initial dx invasive dc 2 cm lump, age 39
lumpectomy & 3 of 5 nodes +, ER+/PR+, Her2+++
alternative chemo 5/05-7/05, rad 8/05-10/05
7/06 dx mets to vertebrae, pelvis & chest lymph nodes
8/06 - 10/06 tamoxifen, herceptin, oophorectomy & zometa
11/06 PET/CT showed continued bone mets, new spot on liver
12/06 began taxotere/herceptin 1x/3 weeks,
2/07 - 2-08 NED!
3/08 progression, start taxol/herceptin weekly, monthly zometa
8/08 start ai & herceptin
12/08 - progression, start weekly navelbine/herceptin thru 6/09 & monthly zometa
7/09 - PET/CT showed improvement in spine, but 2-3 lymph nodes in chest became active
9/09 - 11/09 - weekly abraxane/herceptin
12/09 - PET/CT - chest lymph nodes resolved, progression in spine & pelvis
2/10 - 6/10 - start tykerb/xeloda, progession in spine & pelvis
7/10 - start taxotere/carboplatin/herceptin
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