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12-29-2007, 04:54 PM
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#1
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Senior Member
Join Date: Nov 2004
Location: Misty woods of WA State
Posts: 4,128
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Wowee!
Dear Barbara and Lily -
I am a little slow to get over to this part of the forum, but you have both been in my most POSITIVE thoughts and GOOD wishes.
So great to hear good news from you both at a time when we really need it! We know Barbara was a good responder to Herceptin so it was with every bit of faith that you would do will in this new trial.
KEEP on responding, ladies. Maybe with results like these they can fast-track this drug, and more oncs could use it off-label for those not in a trial area.
__________________
"When I hear music, I fear no danger. I am invulnerable. I see no foe. I am related to the earliest times, and to the latest." H.D. Thoreau
Live in the moment.
MY STORY SO FAR ~~~~
Found suspicious lump 9/2000
Lumpectomy, then node dissection and port placement
Stage IIB, 8 pos nodes of 18, Grade 3, ER & PR -
Adriamycin 12 weekly, taxotere 4 rounds
36 rads - very little burning
3 mos after rads liver full of tumors, Stage IV Jan 2002, one spot on sternum
Weekly Taxol, Navelbine, Herceptin for 27 rounds to NED!
2003 & 2004 no active disease - 3 weekly Herceptin + Zometa
Jan 2005 two mets to brain - Gamma Knife on Jan 18
All clear until treated cerebellum spot showing activity on Jan 2006 brain MRI & brain PET
Brain surgery on Feb 9, 2006 - no cancer, 100% radiation necrosis - tumor was still dying
Continue as NED while on Herceptin & quarterly Zometa
Fall-2006 - off Zometa - watching one small brain spot (scar?)
2007 - spot/scar in brain stable - finished anticoagulation therapy for clot along my port-a-catheter - 3 angioplasties to unblock vena cava
2008 - Brain and body still NED! Port removed and scans in Dec.
Dec 2008 - stop Herceptin - Vaccine Trial at U of W begun in Oct. of 2011
STILL NED everywhere in Feb 2014 - on wing & prayer
7/14 - Started twice yearly Zometa for my bones
Jan. 2015 checkup still shows NED
2015 Neuropathy in feet - otherwise all OK - still NED.
Same news for 2016 and all of 2017.
Nov of 2017 - had small skin cancer removed from my face. Will have Zometa end of Jan. 2018.
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12-29-2007, 10:30 PM
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#2
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Member
Join Date: Nov 2007
Location: Minneapolis, MN
Posts: 20
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PTL It's WORKING!!!!!!!!!!!!!
Hi Ladies,
Just wanted to update you. My scans looked great the neck nodes have skriked in to half the size they where. No new ones! Liver is stable, just a little progession in the hips and spine. Not surprised I am sore more often. So I am going into 08 rip roaring to go!!!
God has truly blessed me so many times through this joruney. I am so humbled and grateful for all his love and my friends! Also all of you have been so full of Grace for me. Thank you and have a peace filled new year!
__________________
MPB
IDC in 1996 Stage 3 Grade D 17 pos. nodes
2003 liver mets found HER2 Her/Taxol then did the first trail for Trykerb and Xelosa until 11-07
Six new tumors on neck will be starting the MCC_DM1 trail this week.
"Believe in miracles, and watch them happen!"
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12-30-2007, 07:38 PM
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#3
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Senior Member
Join Date: Aug 2001
Location: Oregon
Posts: 1,756
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Barbara, Lily and Marsha,
Great news on your scan results!!! As Marsha above says, go into '08 rip roaring!
<3 Lolly
__________________
Sept.'99 - Dx.Stage IIIB, IDC ER/PR-, HER2+++ by IHC, confirmed '04 by FISH. Left MRM, AC x's 4, Taxol x's 4, 33 Rads, finishing Tx May 2000. Jan.'01 - local/regional recurrence, Stage IV. Herceptin/Navelbine weekly till NED August 2001, then maintenance Herceptin. Right Mast. April 2002. Local/Regional recurrence April '04, Herceptin plus/minus chemo until May '07. Gemzar added from Feb.'07-April '07; Tykerb/Abraxane until August '07, back on Herceptin plus Taxotere and Xeloda Sept. '07. Stopped T/X Nov. '07, stopped Herceptin Dec. '07, started Avastin/Taxol/Carboplatin Dec. '07. Progression in chest skin, stopped TAC March '03, started radiation.
Herceptin has served as the "Backbone" of my treatment strategy for over 6 years, giving me great quality of life. In 2005, I was privileged to participate in the University of Washington/Seattle HER2 Vaccine Trial.
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12-30-2007, 07:59 PM
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#4
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Senior Member
Join Date: Sep 2005
Location: Newton, MA
Posts: 951
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For MPB
Hi MPB,
You may just be sore. In the beginning the bone scans can show progression even when the cancer is not progressing. You will probably need to wait for a few more scans before you can determine what is going on. I have been on the trial since September and the CT and bone scan is finally showing response to treatment.
This is what my most recent CT scan on 12/20 indicated:
"Metastatic involvement of the bones is apparent, with areas of increasing sclerosis in comparison to prior study, possibly a treatment effect."
My bone scan indicated: There has been a slight decrease in the intensity of the radiotracer uptake associated with lesions in the right clavicle and the right hemipelvis. The additional lesions, including the one in the T11 and L1 vertebral bodies appear unchanged.
While this does not sound great, my tumor markers are now normal, and they are an excellent benchmark for me. I have the sense that it takes a while for these scans to show measurable response in the bones.
Best wishes,
Barbara H.
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01-23-2008, 03:10 PM
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#5
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Senior Member
Join Date: Nov 2007
Posts: 210
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barb.. how has your treatment been going.. long time no hear...
runtolive
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01-25-2008, 04:22 PM
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#6
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Senior Member
Join Date: Sep 2005
Location: Newton, MA
Posts: 951
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Everything is going well. I had a CT scan and bone scan today. There is really no news and nothing to post until I receive the results of these tests.
Thanks for thinking of me.
Barbara
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01-26-2008, 07:39 AM
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#7
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Senior Member
Join Date: Jul 2005
Location: Ft. Collins, Colorado
Posts: 546
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can't wait to hear
the good news!
__________________
with love and gratitude,
joy
dx stage I 2/2000*er/pr+; her- per IHC*lumpectomy*4 rounds A/C*30 rads*tamoxifen*dx stage 4 5/2002*huge mets to liver*tiny mets to lungs*stopped tamoxifen*5/02 taxotere/xeloda*her 2 checked with FiSH-her2+++herceptin *2/03 stopped chemo femara w/herceptin*zolodex*04 switched to aromasin w/herceptin*05 high estrogen tx*11/05taxol/carbo*7/06 stopped chemo; megace/herceptin*9/06navelbine/herceptin*5/07tykerb/xeloda great response*4/08 progression in liver; ooph/ faslodex /herceptin
6/08 began Herceptin DM-1
9/08 progression
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01-27-2008, 06:43 AM
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#8
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Senior Member
Join Date: Nov 2007
Posts: 210
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hopefully the drug wipes out all the pain in your bones... like you say .. feels like its working. stay strong..
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01-15-2008, 09:41 AM
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#9
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Senior Member
Join Date: Nov 2007
Posts: 210
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marsha.. how was your first treatment..
runtolive
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