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Old 07-01-2007, 02:19 PM   #1
AlaskaAngel
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Possible connection

If tea consumption drops significantly in Japanese women who adopt more of a western diet.... tea may be a significant key to that puzzle as well.

Thanks, Robin.

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Old 07-05-2007, 02:47 PM   #2
StephN
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Question Tea or other?

Hi -
This is interesting and I do use as many pathways as I feel have been shown to be blocked by competent studies. Had not heard of the FAS/black tea thing.

I have been off caffeine for years - since mets diagnosis. Only get a little from the organic dark chocolate I nibble on.

Wonder if there is another food item that would work against the FAS that we are not yet talking about??

I feel that dietary changes plus Herceptin have worked to keep me in long remission. I am pretty religious about those changes.
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MY STORY SO FAR ~~~~
Found suspicious lump 9/2000
Lumpectomy, then node dissection and port placement
Stage IIB, 8 pos nodes of 18, Grade 3, ER & PR -
Adriamycin 12 weekly, taxotere 4 rounds
36 rads - very little burning
3 mos after rads liver full of tumors, Stage IV Jan 2002, one spot on sternum
Weekly Taxol, Navelbine, Herceptin for 27 rounds to NED!
2003 & 2004 no active disease - 3 weekly Herceptin + Zometa
Jan 2005 two mets to brain - Gamma Knife on Jan 18
All clear until treated cerebellum spot showing activity on Jan 2006 brain MRI & brain PET
Brain surgery on Feb 9, 2006 - no cancer, 100% radiation necrosis - tumor was still dying
Continue as NED while on Herceptin & quarterly Zometa
Fall-2006 - off Zometa - watching one small brain spot (scar?)
2007 - spot/scar in brain stable - finished anticoagulation therapy for clot along my port-a-catheter - 3 angioplasties to unblock vena cava
2008 - Brain and body still NED! Port removed and scans in Dec.
Dec 2008 - stop Herceptin - Vaccine Trial at U of W begun in Oct. of 2011
STILL NED everywhere in Feb 2014 - on wing & prayer
7/14 - Started twice yearly Zometa for my bones
Jan. 2015 checkup still shows NED
2015 Neuropathy in feet - otherwise all OK - still NED.
Same news for 2016 and all of 2017.
Nov of 2017 - had small skin cancer removed from my face. Will have Zometa end of Jan. 2018.
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Old 07-06-2007, 06:28 AM   #3
Joy
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what about if you are also Er/Pr+

this is always an area which confounds me. I am triple postive, I guess still, and sometimes what inhibits in Her2 positivity is proliferative in er positivity. I never know which of these things I should do and I AM willing to do these things and have done in the past, but then got so confused between drug interactions and the intricacies of pathology. Thoughts?

thank you!
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dx stage I 2/2000*er/pr+; her- per IHC*lumpectomy*4 rounds A/C*30 rads*tamoxifen*dx stage 4 5/2002*huge mets to liver*tiny mets to lungs*stopped tamoxifen*5/02 taxotere/xeloda*her 2 checked with FiSH-her2+++herceptin *2/03 stopped chemo femara w/herceptin*zolodex*04 switched to aromasin w/herceptin*05 high estrogen tx*11/05taxol/carbo*7/06 stopped chemo; megace/herceptin*9/06navelbine/herceptin*5/07tykerb/xeloda great response*4/08 progression in liver; ooph/ faslodex /herceptin
6/08 began Herceptin DM-1
9/08 progression
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Old 07-06-2007, 11:53 AM   #4
RobinP
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Joy, you want to block the er and her2, her3 pathway simultaneously. I think that is possible to some degree with diet as turmeric and black tea block the er pathway; green tea, black tea, omega threes fatty acids, ALA and GLA block the her2 pathway; and finally black tea also blocks one of her2's major heterdimerizing partners, her3.

http://her2support.org/vbulletin/showthread.php?t=28953

Most people don't know if they are her1+, unless they've gone out of their way to be tested.However, to those who are her1+, a natural inhibitor MAY be genistein and other isoflavons:
http://www.freepatentsonline.com/6638543.html
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