Tom, more on the mechanism of Herceptin cardiotoxicity

[Tom]

That was another great article Lani. I find the whole ERB family of receptors truly fascinating. This is good stuff and worth doing additional research on when I have a minute. I have wondered a lot about the unknown effects of inhibiting tyrosine kinase. I have used the green tea and green tea supplements to produce tyrosine kinase inhibition via EGCG, in the transcellular domain. I want to see if I can find additional effects that might have on normal body function. I am also attempting to inhibit PI3K with inositol hexaphosphate, so that is yet another area to look at for unknown benefits/side effects.


Tom