taxol & avastin & short of breath???

[Pam P]

I've been on taxol & avastin since May. I have bone mets. The combo is working - ca2729 has come down almost 500 pts.

The issue is for the last month or so I've been noticing shortness of breath & it seems to be getting worse -- or I'm more obsessed with it -- not sure which.

This chemo has caused my hemoglobin to be quite low - last time 8.9. also my b/p has risen to the point where I might have to go on b/p meds.

Has anyone had shortness of breath with taxol or avastin? From low hemoglobin or high b/p?

Maybe pleural effusions? I had that as a result of taxotere. I needed thoracentisis 4 times, but no cancer cells found in the fluid. Do people get p/e from taxol?

I don't think it likely to be lung met with my tumor markers coming down. Could it be heart related?

I see my oncologist next week & will certainly ask him. But I'd like to know if you've had this on this chemo ... and what you think could be going on.

Thanks. Pam