" Our data strongly suggest that selected pts with HER2+ tumors may not need chemo"

[Basilic]

Update - Neoadjuvant treatment of Herceptin and Tykerb

I completed my Herceptin/Tykerb treatment at the end of June and had my surgery July 3rd. The cancer was not completely cleared as I had hoped but all that remained of that very large tumor (>7 cm) were two small nodules less than .8 cm each. I had 27 lymph nodes removed and only 4 of those still had cancer. It's difficult to depict how many lymph nodes were originally malignant from the MRI, but more than likely I had a lot more than 4 when I started. The important thing is that I had good clear margins. I start AC on August 16.

Overall, my reponse was great compared to where I started from.

Stage IIIb/with IBC
grade 3 tumor
negative ER/PR
> 7 cm
Her2++ (I think ratio was 11.8)