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A warning, about ovarian suppression and AIs....
I've seen lots of posts here recently about ovarian suppression (which I am doing, zoladex shots) and women taking AIs. My oncologist has always refused to give them to me without my ovaries out, thus I've been taking the dreaded "T" drug being her2 positive, which has always bothered me.
Now, I'm actually glad.
I have a friend with metastatic BC in Kansas City who was on lupron for 15 months and AIs (forget which one). Well, in the 15th month her period started! They tested her estridol levels, and sure enough she was premenopausal. I didn't know that could happen. So the AIs were not effective, and her cancer had spread in those last few months. When she went to get her ovaries out the next month, they found cancer in BOTH of her ovaries.
Be very very careful if you are on AIs without your ovaries out. Check for any signs of ovulation and get those levels checked. Better yet, just have the surgery and be done with it.
Rose
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Rose
Dx'd 1/04 at 33, while 33 weeks pregnant
Dx: Stage IIIC IDC, ER-, PR+ (23%), Her2=2.7 (IDC)/7.6 (FSH), 2.5cm primary tumor, grade III, 11/18+ nodes (largest 3.8 cm)
Treatment: A/C *4, T *4, 1 year of herceptin (BCIRG 006), mastectomy, rads (7 weeks), zoladex (5 years) with tamoxifen (2 years)/aromisin (3 years), bilateral SGAP summer 05 at NOLA
Oops, retested tumor and I guess I'm er/pr- after all.
Stopped all hormonal tx 10/07. Periods resumed 6/08. Bye bye hot flashes!!!!
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