AI's, etc effect on estradiol
Question,
Has there been clear differentiation made on how the various AI's and tamoxifen target the various kinds of estrogen? In particular, targeting estradiol, which I believe is the most dangerous estrogen. While doing a google search I was shocked to see loads of body-building forums talking at great length about taking estrogen suppressing drugs; the exact same drugs bc patients take: tamoxifen, arimidex, aromasin, etc. While I know this is an EXTREMELY dubious souce of info, and I am appalled at what these people do for vanity, one post impied that aromasin was more effective at lowering estradiol than arimidex, which he/she claimed more targeted estrone. (these crazy people are doing bloodwork on a very frequent basis) I am interested if there is any scientific validity in this statement.
Thanks
TRS
__________________
Terri, spouse of Ruth, Dallas/Ft. Worth area
Ruth dx 05/01/07 (age 50) Filipino
multifocal, several tumors .5 -2.5 cm, large area
Breast MRI showed 2 enlarged nodes, not palpable
100%ER+, 95%PR+, HER2+++
6x pre-surgery TCH chemo finished 9/15/7 Dramatic tumor shrinkage
1 year Herceptin till 6/08
MRM 10/11/07, SNB: 0/4 nodes + Path: tumors reduced to only a few "scattered cells"
now 50% ER+, PR- ???
Rads finished 1/16/08
Added Tamoxifen,
Finished Herceptin 05/08
NOW is the time to appreciate life to the fullest.
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