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Old 02-05-2009, 05:41 AM   #1
Pam P
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Join Date: Sep 2005
Location: MN
Posts: 731
success with abraxane after taxol?

I've been on taxol/avastin for 9 months. My ca2729 continues to rise (322 is latest). Scans don't show change. My onc. said my choices are abraxane, gemzar, ixempra. He was leaning to abraxane and will add herceptin or tykerb instead of the avastin.

I will be happy to get off the avastin because of the b/p and other side effects for me. I see the cardiologist on Fri. and will have an echo. If my lvef is high enough I think my onc. will choose herceptin. But I think the tykerb because it passes the blood brain barrier - is there a better reason to go with herceptin? My onc. likes it because there's more data on it.

Has anyone done abraxane following taxol? I know it's in the same family... so that that mean it might not be as effective as a different chemo? I don't see the the onc. until 2/18 to make a decision.

I had a treatment scheduled yesterday. But I woke up so sick - achy, chills, headache, the whole deal. I didn't feel like trying to get up so I cancelled! I've gone many times before not feeling well with a cold. First time in over 7 yrs I've done that - sort of feel guilty. I think only 1 other time did I not get chemo as my counts were too low.
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Pam
6/01 IBC er+ her2+stage IIIb; mastecomy
7/01 AC, taxol; radiation
2/02 tamoxifen
9/02 stage IV bone mets femara
1/03 taxotere/herceptin/aredia
6/03 herceptin, aredia & faslodex
1/04 navelbine, herceptin, aredia
2/05 herceptin/aredia
7/05 xeloda/herceptin/aredia
3/07 xeloda/tykerb/aredia
5/08 taxol/avastin/aredia
2/09 gemzar/herceptin/zometa
7/09 Taxol/Carbo/Herceptin, zometa
10/09 navelbine/herceptin & zometa
2/10 herceptin & tykerb & zometa
4/10 add xeloda &aromasin
10/10 dx with dermatomyiositis triggered by cancer
11/10 restart herceptin, tykerb, zometa
12/10 surgery-place rod in R femur to stabilize bone
1/11 radiation to R femur - 20 tx
2/11 2nd surgery - rod in Left femur
2/11 tx eribulen -- suspended dx brain mets
3/11 brain mets wbr 20 tx
4/11 halaven; discontine 8/11 not working
8/11 radiation to left femur 20 tx'
8-9/11 rad to lower spine
9/11 abraxane/herceptin/zometa
9/12 xeloda/herceptin/zometa
12/12 ablation of liver
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