Update from chrisy on dm1 response
Hi friends,
I want to share some good news with you! After a short bout of post scanxiety inscanity (caused by a communication breakdown - my NP thought her coworker had called me and so didn't call me herself. Which I of course interpreted as SHE DOESN'T WANT TO CALL ME BECAUSE THE NEWS IS SOOOOOO BAD)...
My PET/CT scan results after my #8 infusion of T-DM1 reads as follows:
bla bla bla bla bla blabla bla bla bla bla blabla bla bla bla bla blabla bla bla bla bla blabla bla bla bla bla blabla bla bla bla bla bla
IMPRESSION:
1. The previously seen lesion within the anterior dome of the liver is less well seen and is now isointense with liver with a maximum SUV value of 3.1.
2. (WAIT FOR IT........)
No evidence of metastatic disease is seen on the current examination.
HOLY S#%T!!!!!!
BTW, the report also noted multiple body areas as "unremarkable", including my brain, so we know it's an accurate scan!
Kidding aside, this drug is a great drug - I had to fight to stay on the study because of high LFT's, and I'm so glad I did!
Much love to all
Chris
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Chris in Scotts Valley
June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial
5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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