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Old 11-06-2012, 06:38 AM   #1
Jean
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Chloroquine...interesting.

http://www.medicalnewstoday.com/releases/252344.php

I have always found it amazing how one drug designed for one medical reason ends up solving another medical
problem.

If only....this could be the answer.
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ER+ 90% / PR-, Her2+++ by FISH
Ki-67 40%
Arimidex 5/05
Radiation 32 trt, 5/30/05
Oncotype DX test 4/17/06, 31% high risk
TOPO 11 neg. 4/06
Stopped Arimidex 5/06
TCH 5/06, 6 treatments
Herceptin 5/06 - for 1 yr.
9/06 Completed chemo
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Old 11-06-2012, 09:04 AM   #2
NanaJoni
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Re: Chloroquine...interesting.

I took this drug years ago for lupus - brand name Plaquenil. It would be wonderful if it has success against cancer.
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3/01/10: found lump in rt.breast
3/12/10: mammogram/ultrasnd/biopsy-invasive bc & DCIS; 2 tumors (2cm er-/pr-/HER2-& 1.8 cm er-/pr-/HER2+); grade 3;poorly differentiated
3/24/10:sent.node biopsy clear
3/31/10:bi-lateral mx.;atypical ductal hyperplasia-lft side
4/21/10:wound revision-infection/scarring 4/28/10:seromas both sides
5/21/10:port installed,TCH chemo (6 x 3 wks); Herc,-1yr; 33 rad tx after chemo
07/2010: port not working-2nd port didnt'work;3rd port opposite side.
07/2010: 2 weeks after 3rd port surgery, threw 3 pulm. emboli-IVC filter installed; warfarin
08/2010: hospitalizations w/3 of chemos; decision to stop after 4th-on to radiation in Oct 2010;Herc cont.
12/03/2010 - finished 33 rads Hooray!! cont. Herc. every 3 wks
4/2011 - pneumonia ??? Nope-radiation pneumonitis. No more Herc.
5/2011 - NED!!! port out.
8/2011 - clean PET & CT scans.Still NED
7/2012 - Still NED/very blessed.
2/2013 - 6 mos checkup-all clear. CA2729 down frm 13 to 11.
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Old 11-06-2012, 09:11 AM   #3
Lani
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Re: Chloroquine...interesting.

I have posted on chloroquine before--and Courtney even tried it. As I recall she developed a seizure attributed to the chloroquine, one of the reasons physicians are hesitant about "off-label" use.
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Old 11-06-2012, 11:52 AM   #4
sarah
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Re: Chloroquine...interesting.

yes, very interesting
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Old 11-07-2012, 05:18 AM   #5
Ellie F
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Re: Chloroquine...interesting.

Hi
Lani your right our Courtney did take this prescribed by her onc but as you say had a seizure. It seems a pity that there arn't clinical trials looking at its effectiveness. I guess there's no money to be made.
Ellie
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Old 11-07-2012, 09:35 AM   #6
Lani
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Re: Chloroquine...interesting.

Dr. Lance Liotta started the trial of "neoadjuvant" chloroquin for DCIS and plans others. Heard him speak about them in 2011. Will try to catch up with his latest at the upcoming meetings.
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Old 11-09-2012, 10:03 AM   #7
KristinSchwick
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Re: Chloroquine...interesting.

I emailed Courtney about Chloroquin, and after her experience she firmly told me NOT TO TAKE it. She said it was NOT worth the risk- she said she was constantly worried about having a seizure while driving or when she was in the shower or home alone. God Bless our lost sister, I miss her spirit.
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Aug 2010: diagnosed stage 3b, 4 mo. after birth of son. 29 yrs old and breastfeeding, ER/PR-, Her-2+ started Neoadjuvant therapy: 4x FEC, 10x abraxane & Herceptin
Feb 2011: L mx with recon. Path. showed only DCIS but 4/10+ nodes.
March 2011: 6 wks rads.
Mother passed, lower back pain.
Late May 2011: Bone mets but organs clear; Tykerb, Xeloda, Xgeva. Stopped Herceptin. Implant infected: removed implant.
October 2011: Bone progression; Gemzar and Carboplatin & restarted Herceptin.
Jan 2012: Progression, re-classified as ER+; Tykerb, Herceptin, Zoladex & Femara. Anti-E is working!
May 2012: ovaries out, markers stable but elevated. Cont. Herceptin, Tykerb, Xgeva & Femara.
Dec 2012: aromasin
Jan 2013: faslodex, herceptin, tykerb
Jun: Kadcyla
Aug: Rads to hip, then Perjeta, Herceptin & Taxotere
Nov 2013: Perjeta, Herceptin, Halaven
Early 2014: Affinitor, Aromasin, Perjeta, Herceptin.
June 2014: Estradiol, Perjeta, Herceptin
Aug 14: Tamoxofin, H & P
http://kristin-notdying-blog.blogspot.com/
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