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Old 03-06-2008, 07:39 PM   #1
Ceesun
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Question Vaccine Trial

Please explain what this is? Who qualifies? Is this given along with treatment? Thanks Ceesun
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Old 03-07-2008, 07:19 PM   #2
Sheila
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I know Michelle U did this, and Lolly and I can't remember who else...they had it in Seattle....there was also one in Washington DC...hopefully they will respond
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Diagnosed at age 49.99999 2/21/2002 via Mammography (Calcifications)
Core Biopsy 2/22/02
L. Mastectomy 2/25/2002
Stage 1, 0.7cm IDC, Node Neg from 19 nodes Her2+++ ER PR Neg
6/2003 Reconstruction W/ Tissue Expander, Silicone Implant
9/2003 Stage IV with Mets to Supraclavicular nodes
9/2003 Began Herceptin every 3 weeks
3/2006 Xeloda 2500mg/Herceptin for recurrence to neck nodes
3/2007 Added back the Xeloda with Herceptin for continued mets to nodes
5/2007 Taken Off Xeloda, no longer working
6/14/07 Taxol/Herceptin/Avastin
3/26 - 5/28/08 Taxol Holiday Whopeeeeeeeee
5/29 2008 Back on Taxol w Herceptin q 2 weeks
4/2009 Progression on Taxol & Paralyzed L Vocal Cord from Nodes Pressing on Nerve
5/2009 Begin Rx with Navelbine/Herceptin
11/09 Progression on Navelbine
Fought for and started Tykerb/Herceptin...nodes are melting!!!!!
2/2010 Back to Avastin/Herceptin
5/2010 Switched to Metronomic Chemo with Herceptin...Cytoxan and Methotrexate
Pericardial Window Surgery to Drain Pericardial Effusion
7/2010 Back to walking a mile a day...YEAH!!!!
9/2010 Nodes are back with a vengence in neck
Qualified for TDM-1 EAP
10/6/10 Begin my miracle drug, TDM-1
Mixed response, shrinking internal nodes, progression skin mets after 3 treatments
12/6/10 Started Halaven (Eribulen) /Herceptin excellent results in 2 treatments
2/2011 I CELEBRATE my 9 YEAR MARK!!!!!!!!!!!!!
7/5/11 begin Gemzar /Herceptin for node progression
2/8/2012 Gemzar stopped, Continue Herceptin
2/20/2012 Begin Tomo Radiation to Neck Nodes
2/21/2012 I CELEBRATE 10 YEARS
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6/28/12 Stopped Taxotere due to pregression, Started Perjeta/Herceptin
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Old 03-07-2008, 08:12 PM   #3
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There are many trials for a vaccine:

http://www.clinicaltrials.gov/ct2/re...her2&flds=Xabe


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Old 03-07-2008, 09:44 PM   #4
Margerie
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Ceesun,

I also particpated in the Univ of WA tumor vaccine trial. I believe you have to be originally diagnosed stage 3 or 4, and currently NED (or close). Here is a link to their trials. They were very helpful when I originally emailed requesting information. For the trial I am enrolled in, I had to fly to Seattle 7 times in a 15 month period. My last visit is next Friday.

Here is the link to their trials:
http://depts.washington.edu/tumorvac/trials.php
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MRM, 4 DD A/C, 12 weekly taxol + herceptin
rads concurrent with taxol/herceptin
finished herceptin 01/08
ooph, Arimidex, bilateral DIEP reconstruction
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Univ. of WA, Seattle vaccine trial '07
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Old 03-07-2008, 10:00 PM   #5
goops
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I wish they offered these vaccine trials near me - did you have any side effects from the vaccines?

What do they mean by maintenance dose of Herceptin?
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