Bad heart news.....wah!!!!!!!!

[7andcounting]

Hello All,

Well the fun just never stops. Just when I think I know the plan, life springs new things on me.

I just got through jumping through all the hoops to qualify to be on the TDM-1 trial. Got my tissue sample verified that I was Her2+, had every scan imaginable and thought I was all set to be randomized to one of the arms of the trial, when I got a call that my heart function was very low.

Shock!

I have been having echos every 3 months and all was fine. I asked to have a MUGA to confirm that the echo was correct, b/c it didn't seem possible that my heart function could have deteriorated that much, but the MUGA confirmed that it was indeed true.

My question is: Has anyone had their heart function drop significantly, then gone off Herceptin for a few months and then had their heart return to better levels that let them resume their Her2+ targeted therapies?

Any insight is appreciated!

Thanks!