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Old 04-05-2006, 07:38 PM   #1
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Question Abraxane - most common side effects??

For anyone that knows about Abraxane, what are the most common side effects?

~ hair loss?
~ nausea?
~ flu-like symptoms?

Thanks in advance!
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Old 04-05-2006, 08:53 PM   #2
Yorkiegirl
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I had 4treatments of Abraxane. I already had the Hair loss from the 4 X AC/


I never had any nausea, I had diarrhea real bad, and was real tired, I did had low RBC two times. I did have joint and muscle pain but it did go away.

I was looking at my hand out sheet and this is what they list could be some side effects:

Hair Loss, Low WBC, Low RBC, fatigue, nausea, vomiting , joint and muscle pain.
fever, infection, tingling of hands and feet, headache, heart rhythm abnormalities, low blood platelet count.

They should give you hand out sheet to read and go over and sign, WELL at least they at my Center, I have to sign a consent form for any treatment and sign a form I have read and asked any questions on the drug I am being given. They keep a copy and I get a copy.

Heck my binder is getting so full with all of my paper work I have. LOL

Vicki
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Old 04-06-2006, 04:34 AM   #3
IRENE FROM TAMPA
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Abraxane Side Effects

I started on Abraxane in July of 2005 (was just taken off).

The only side effects I had was some neuraphy (?) of the hands and feet and a not really extremely bad. (I went bowling last nite so not too bad)

My counts have actually been better then on any other chemo I have taken. Never experienced any nausea or diarhea. Had hair loss of course.

For me I have to say has not been a bad drug to take.

I hope you have same experience and good luck.
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Irene from Tampa
1996 - INFILT DUCTAL CAR.W/ LYMPH NODE INVOLVEMENT. ADRIA/CYTOXIN/5FU
1999 - RECURR. TO AUXILA AND 2 TUMORS IN LIVER
TREAT: STEM CELL REPLACEMENT/HERCEPTIN.
2002 - RECUR TO LIVER
TREAT: NAVELBINE, THEN GEMZAR, THEN XELODA.
2004 - TUMORS STILL IN LIVER
TREAT: RFA TO LIVER
STABLE UNTIL
2004 - TUMOR PROGRESSION IN LIVER.
TREAT: RESECT HALF OF LIVER.
2005 - RECURR TO LYMPH NODE OUTSIDE OF LIVER.
TREAT: TAXOL/CARPO/HERCEPTIN. FAILED ON
THIS TRIO. STARTED ON ABRAXANE.
2006 - PROGRESS WITH 2ND TUMOR GROWTH.
TREAT: AUG. BEGAN ON TYKERB/XELODA
TRIAL. CONSIDERED STABLE TO DATE.
2007 - TAKEN OFF OF TYKERB/XELODA TRIAL DUE TO
PROGRESS STARTING TYKERB/AVASTIN.
NOV 2007 - SCANS SHOW PROGRESS TUMOR GROWTH
IN ABDOM. AND TWO NEW TUMORS IN NECK AREA.
BEGAN HERCEPTIN/AVASTIN/TAXOTERE
Feb 08 - Ixempra/Xeloda
June 08 - Her/DM1 trial

"I WANT TO BE AN OUTRAGEOUS OLD WOMAN WHO NEVER GETS CALLED AN OLD LADY. I WANT TO GET SHARP EDGED & EARTH COLORED, TILL I FADE AWAY FROM PURE JOY."
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Old 04-06-2006, 09:40 AM   #4
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Cool Irene

Thanks so much for your replies.

I was confused about the most common side effects of Abraxane. One website listed things, but another didn't include hair loss. Looks like Abraxane causes hair loss. :-(

Irene, why were you taken off Abraxane? Are you on any other chemos presently?

Good luck to all!
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Old 04-06-2006, 08:11 PM   #5
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Well at present my tumor marker (CEA) is on the rise and that is a pretty good indicator for me that something is stirring again. So it may be that the Abraxane has stopped working for me. I have just rescanned and will get results next week and on to the next drug. I am not sure until we find out what is going on what I will do next.

My onc just decided to stop the Abraxane until we see what is actually happening.

Take care.
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Old 04-06-2006, 08:14 PM   #6
IRENE FROM TAMPA
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to unregistered from Irene

sorry I forgot to register before I answered your question, but the prior response was from me

Irene
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Irene from Tampa
1996 - INFILT DUCTAL CAR.W/ LYMPH NODE INVOLVEMENT. ADRIA/CYTOXIN/5FU
1999 - RECURR. TO AUXILA AND 2 TUMORS IN LIVER
TREAT: STEM CELL REPLACEMENT/HERCEPTIN.
2002 - RECUR TO LIVER
TREAT: NAVELBINE, THEN GEMZAR, THEN XELODA.
2004 - TUMORS STILL IN LIVER
TREAT: RFA TO LIVER
STABLE UNTIL
2004 - TUMOR PROGRESSION IN LIVER.
TREAT: RESECT HALF OF LIVER.
2005 - RECURR TO LYMPH NODE OUTSIDE OF LIVER.
TREAT: TAXOL/CARPO/HERCEPTIN. FAILED ON
THIS TRIO. STARTED ON ABRAXANE.
2006 - PROGRESS WITH 2ND TUMOR GROWTH.
TREAT: AUG. BEGAN ON TYKERB/XELODA
TRIAL. CONSIDERED STABLE TO DATE.
2007 - TAKEN OFF OF TYKERB/XELODA TRIAL DUE TO
PROGRESS STARTING TYKERB/AVASTIN.
NOV 2007 - SCANS SHOW PROGRESS TUMOR GROWTH
IN ABDOM. AND TWO NEW TUMORS IN NECK AREA.
BEGAN HERCEPTIN/AVASTIN/TAXOTERE
Feb 08 - Ixempra/Xeloda
June 08 - Her/DM1 trial

"I WANT TO BE AN OUTRAGEOUS OLD WOMAN WHO NEVER GETS CALLED AN OLD LADY. I WANT TO GET SHARP EDGED & EARTH COLORED, TILL I FADE AWAY FROM PURE JOY."
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Old 04-07-2006, 03:37 PM   #7
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Question Abraxane Infusion Schedule?

One more question... can you tell me how frequent you have had Abraxane? Thanks!
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Old 04-07-2006, 03:47 PM   #8
IRENE FROM TAMPA
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Thumbs up To unregistered

No problem, you can ask me as many questions as you like.

I asked if I could take the Abraxane weekly at a smaller dose which my onc. agreed on since I had taken so many different chemos prior, we were not sure how my counts would tolerate it.
I took a dose weekly for three weeks and then I had one week off. I tolerated it very well.

Hope everything goes well for you and like I said if I can answer any other questions, I would love to.
__________________
Irene from Tampa
1996 - INFILT DUCTAL CAR.W/ LYMPH NODE INVOLVEMENT. ADRIA/CYTOXIN/5FU
1999 - RECURR. TO AUXILA AND 2 TUMORS IN LIVER
TREAT: STEM CELL REPLACEMENT/HERCEPTIN.
2002 - RECUR TO LIVER
TREAT: NAVELBINE, THEN GEMZAR, THEN XELODA.
2004 - TUMORS STILL IN LIVER
TREAT: RFA TO LIVER
STABLE UNTIL
2004 - TUMOR PROGRESSION IN LIVER.
TREAT: RESECT HALF OF LIVER.
2005 - RECURR TO LYMPH NODE OUTSIDE OF LIVER.
TREAT: TAXOL/CARPO/HERCEPTIN. FAILED ON
THIS TRIO. STARTED ON ABRAXANE.
2006 - PROGRESS WITH 2ND TUMOR GROWTH.
TREAT: AUG. BEGAN ON TYKERB/XELODA
TRIAL. CONSIDERED STABLE TO DATE.
2007 - TAKEN OFF OF TYKERB/XELODA TRIAL DUE TO
PROGRESS STARTING TYKERB/AVASTIN.
NOV 2007 - SCANS SHOW PROGRESS TUMOR GROWTH
IN ABDOM. AND TWO NEW TUMORS IN NECK AREA.
BEGAN HERCEPTIN/AVASTIN/TAXOTERE
Feb 08 - Ixempra/Xeloda
June 08 - Her/DM1 trial

"I WANT TO BE AN OUTRAGEOUS OLD WOMAN WHO NEVER GETS CALLED AN OLD LADY. I WANT TO GET SHARP EDGED & EARTH COLORED, TILL I FADE AWAY FROM PURE JOY."
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