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Old 03-13-2008, 12:54 PM   #1
MJo
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Join Date: Apr 2006
Location: Wilmington, Del.
Posts: 1,126
I need some opinions

My oncologist asked me if I want to be in a clinical trial on aromatase inhibitors. I have taken arimidex for two years. I would switch to Femara for the next three years (the good thing is that I would receive it for free). At the end of three years, I will have been on aromatase inhibitors for a total of five years. Then I would continue taking Femara or a placebo for 5 more years. I would not know if I was taking a placebo.
The study is to find out if 10 years is better than 5. In other words, do a significant amount of women develop metastasis after stopping aromatase inhibitors? Do I want to become a guinea pig? Is five years still the standard for AI? If am going to stop the medicine anyway in five years, why not join the study? I'm just afraid that doctors will continue BC survivors on AI after five years, while I'm on a sugar pill without knowing it and putting myself at risk of recurrence.
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MJO

IDC, Stage I, Grade 2
Oncotype DX Score 32
Her2++ E+P+, Node Neg.
Lumpectomy 11/04/05 Clear Margins
3 Dose dense AC (Couldn't tolerate 4)
4 Dose dense Taxol & Herc. (Tolerated well)
36 weeks Herceptin (Could not complete one year due to decrease in MUGA score)
2 years of Arimidex, then three years of Femara
Finished Femara May 2011
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